Gene Therapy Continues to Benefit Kids with Immunodeficiency
Gene Therapy Continues to Benefit Kids with Immunodeficiency
Four dozen children with severe combined immunodeficiency (SCID) who received a corrective gene carried by a virus have working immune systems two to three years later, according to three independent clinical trials.
Gene Therapy Continues to Benefit Kids with Immunodeficiency
Gene Therapy Continues to Benefit Kids with Immunodeficiency

Four dozen children with severe combined immunodeficiency (SCID) who received a corrective gene carried by a virus have working immune systems two to three years later, according to three independent clinical trials.

Four dozen children with severe combined immunodeficiency (SCID) who received a corrective gene carried by a virus have working immune systems two to three years later, according to three independent clinical trials.

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More SARS-CoV-2 Reinfections Reported, But Still a Rare Event
More SARS-CoV-2 Reinfections Reported, But Still a Rare Event
Ashley Yeager | Oct 26, 2020
Repeat COVID-19 cases could offer clues about people’s immunity to the novel coronavirus and how to vaccinate against it.
How Immune Cells Make the Brain Forget
How Immune Cells Make the Brain Forget
Ashley Yeager | May 1, 2020
Microglia ingest nerve cell connections, leading to the loss of information stored in neuronal circuits.
Image of the Day: Resilient Lung Cells
Image of the Day: Resilient Lung Cells
Nicoletta Lanese | Aug 1, 2019
A specific type of lung cell withstands flu infection by doubling down on DNA repair.
Image of the Day: Gut Response
Image of the Day: Gut Response
Chia-Yi Hou | Jun 24, 2019
Immune functions in the mouse intestine differ by segment.
CAR T Cells Treat Lupus in Mice
CAR T Cells Treat Lupus in Mice
Abby Olena | Mar 6, 2019
T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.
Stick-On Immune Cell Monitor
Stick-On Immune Cell Monitor
Ruth Williams | Mar 1, 2019
A microneedle-containing skin patch offers researchers a noninvasive way to survey immune responses in mice.

Infographic: Immune Cell Monitoring Via a Skin Patch
Infographic: Immune Cell Monitoring Via a Skin Patch
Ruth Williams | Mar 1, 2019
A stick-on patch enables sampling of immune cells in the skin.
Climate Change May Hamper Response to Flu: Study
Climate Change May Hamper Response to Flu: Study
Carolyn Wilke | Feb 5, 2019
Mice exposed to heat wave temperatures ate less and showed weakened immune responses to the virus.
Image of the Day: Brain, Heal Thyself
Image of the Day: Brain, Heal Thyself
The Scientist Staff, The Scientist Staff | Apr 20, 2018
When a mouse’s brain undergoes traumatic injury, immune cells clear the dead from the affected area, after which blood cells swoop in to repair blood vessels.
Chromosomal Instability Drives Cancer Metastasis
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Hungry Macrophages Keep Tattoos on Mice’s Skin
Hungry Macrophages Keep Tattoos on Mice’s Skin
Diana Kwon | Mar 7, 2018
A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.
Maternal Response to Zika Damages Mouse Fetuses
Maternal Response to Zika Damages Mouse Fetuses
Catherine Offord | Jan 5, 2018
Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.
Image of the Day: Hunter Platelets 
Image of the Day: Hunter Platelets 
The Scientist Staff, The Scientist Staff | Dec 19, 2017
Researchers explore how blood platelets sweep bacteria into aggregate bundles at sites of infection to help phagocytic cells dispose of them. 
Newly Discovered Emergency Responders to Liver Damage
Newly Discovered Emergency Responders to Liver Damage
Ashley P. Taylor | Aug 1, 2016
Immune cells called macrophages from the peritoneal cavity of mice migrate to injured livers and aid in repair.
Macrophages Respond to Liver Injury
Macrophages Respond to Liver Injury
Ashley P. Taylor | Jul 31, 2016
In mice, immune cells from the body cavity surrounding organs arrive at the site of damage to chew up the nuclei of dead cells.
Wiping Out Gut Bugs Stops Obesity
Wiping Out Gut Bugs Stops Obesity
Kerry Grens | Nov 16, 2015
In mice lacking intestinal microbiota, white fat turns brown and obesity is prevented.
Time-Lapse on the Cheap
Time-Lapse on the Cheap
Ruth Williams | Feb 1, 2015
A PhD student jury-rigs a microscopy system for high-throughput cell motility assays.