red defocused lights
Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study
Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements.
Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study
Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study

Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements.

Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements.

inflammasomes
close-up of a retina showing blood vessels and a damaged spot
DNA in Cell Cytoplasm Implicated in Age-Related Blindness
Katarina Zimmer | Sep 29, 2021
A new study suggests that DNA synthesized in the cell cytoplasm drives retinal cell death in an advanced form of age-related macular degeneration, a leading cause of blindness.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
an explosion of red light radiating out from a core
Could Curbing Runaway Immune Responses Treat COVID-19?
Shawna Williams | Apr 21, 2020
Drugs targeting patients’ immune systems, rather than the virus itself, could be key to recovery from severe cases of the disease, some researchers suggest.
Image of the Day: Dial M for Murder
The Scientist Staff | Aug 16, 2017
M proteins from Streptococcus bacteria selectively kill mouse macrophages and human macrophage-like cells by prompting cell death.
Protein Clumps Spread Inflammation
Kate Yandell | Jun 22, 2014
ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.
Top 7 in Microbiology
Edyta Zielinska | Sep 26, 2011
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000