3D illustration of a neuron with the cell body highlighted in pink to represent damage from an amyloid β plaque on its axons to the left. An enlarged plaque bundle is shown in the top left corner of the image, with the fibrils highlighted in pink and yellow.

| 5 min read

Amyloid Beta Impairs Microglia Function in Alzheimer’s Disease

Dysregulated lipid metabolism in Alzheimer’s disease causes lipid buildup in microglia, reducing the immune cell’s ability to clear amyloid beta plaques.

Cartoon illustration of a marathon showing blue and grey silhouettes of people running against a city landscape.

| 3 min read

Marathon Running Linked to Short-Term Brain Structure Changes

3D illustration of blue neurons with dendrites extending across the image and overlapping. Several cell bodies of the neurons in the center of the page are highlighted in yellow, red, and orange to depict neurodegenerative pathology.

| 4 min read

Alzheimer’s Disease Affects Tissues Beyond the Brain

lipid

A clipboard with the word “Sepsis” written at the top, surrounded by a syringe and medications.

A Common Antidepressant Protects Organs from Damage During Sepsis

Shelby Bradford, PhD | | 4 min read

Photograph of two polar bears, one walking on an ice shelf and the second emerging from the water.

Hair Oils Prevent Polar Bear Fur from Freezing Up

Shelby Bradford, PhD | | 5 min read

An image of a nose, an organ which is flexible because of a tissue called lipo-cartilage.

The Discovery of a Fat-Filled Cell Reveals Why Noses Are Springy

Sahana Sitaraman, PhD | | 6 min read

A fruit fly (Drosophila melanogaster) sitting on a green grass blade with a green background.

How the Fly Brain Knows When to Release Insulin

Sneha Khedkar | | 4 min read

3D illustration of white Candida albicans yeast cells growing against host tissue.

A Fungal Messenger Impairs Immune Cell Function

Shelby Bradford, PhD | | 3 min read

Move Over, Proteins! Exploring Lipids in Adaptive Immunity

Kamal Nahas, PhD | | 5 min read

three black mice lined up next to each other. the one on the left, fed a low-fat diet, has one small bald patch, the middle mouse, fed fish oil, has a large bald spot across its shoulders and back, and the right mouse, fed cocoa butter, has no baldness.

Fish Oil in Diet Can Cause Hair Loss in Mice, Study Finds

Katherine Irving | | 3 min read

A false color transmission electron microscope micrograph showing the nuclear envelope, the rough endoplasmic reticulum, the nucleus, and the cytoplasm.

New Gene Mutants Identified in Rare Motor Neuron Diseases

Clare Watson | | 2 min read

a brain surrounded by pills

Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study

James M. Gaines | | 4 min read

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An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Auricular vagal neuromodulation therapy is a non-invasive and non-surgical treatment that could aid cardiovascular disease management, Long COVID relief, and more.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

Improved technologies have allowed researchers to delve deeper into T cell biology, but the traditional naming scheme has struggled to keep up with new findings.

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Frogs that freeze themselves solid in the winter and thaw in the spring inspired methods to extend the storage time for transplantable organs.

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue

Research Resources

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

A streamlined, automated process helps scientists coordinate site-ready production-level whole genome sequencing results.

Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

In this webinar, learn how scientists are using cutting-edge spatial proteomics technologies to advance their understanding of cellular organization in healthy and diseased tissues.

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Scientists rely on cytokines, growth factors, and other agents to direct and create different types of organoid models.

Products

Product News

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by next-generation aminooxy chemistry.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

VANTAstar Flexible microplate reader with simplified workflows