macrophages

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.

Whether the finding of a novel mechanism for cancer-related pain can lead to better treatments for neuropathic pain in people remains to be seen.

Erika Moore builds biomaterials to study disparate lupus outcomes.

In mice, a kind of immune memory appears to protect the cells against future harm, a finding that could provide insight into treatments for irritable bowel syndrome and other inflammatory digestive conditions.

Research in mice and humans points to oxidative stress and inflammation as likely drivers of noise-induced health effects such as hypertension and heart disease.

Sound from cars, aircraft, trains, and other man-made machines is more than just annoying. It increases the risk of cardiovascular disease.

Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.

Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.

In a new study, human and mouse cells recognized only one in five bacterial species collected from more than a mile below the Pacific Ocean’s surface.

Researchers find different distributions of the immune cells in young, older, and diseased eyes.

Imaged in real time in living people, immune cells at the surface of the retina could serve as biomarkers to detect retinal and possibly neurological diseases and track their progression.

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

Macrophages transport HIV-like particles into lymph nodes during infection.

Researchers watch cellular interactions in high definition as the immune cells absorb E. coli bacteria.

The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.

From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.