White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
Different Genes Influence Lifespan in Male and Female Mice
Different Genes Influence Lifespan in Male and Female Mice

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

mice
white mouse sitting down
Drug Spurs Neuron Growth in Mice with Chronic Spinal Cord Injury
Natalia Mesa | Sep 27, 2022
A protein duo increases transcription of growth-related genes to enhance axon regeneration and boost plasticity, a study finds—but fails to improve mobility.
Adipose tissue under the microscope appearing as red blobs on a white background
Mouse Brains Appear to Eavesdrop on Their Fat
Alejandra Manjarrez | Sep 9, 2022
For the first time, a team visualizes sensory nerves projecting into adipose tissue in mice and finds these neuronal cells may counteract the local effects of the sympathetic nervous system.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
blue-gloved hands injecting mouse with syringe
Sex of Researcher Influences Ketamine’s Effects in Mice: Study
Shawna Williams | Sep 8, 2022
The findings likely have implications for animal research far beyond the study of antidepressants.
Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid
Internal Clock Disruptions Increase Colon Cancer Risk in Mice
Shafaq Zia | Aug 19, 2022
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
Illustration of bacteriophages infecting a bacterium
Phages Treat Gut Inflammation in Mice
Andy Carstens | Aug 4, 2022
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
multiple generations of family members eating at outdoor table
Sun Exposure Triggers Hunger in Men but Not Women, Study Suggests
Shafaq Zia | Jul 12, 2022
Ultraviolet radiation leads to secretion of an appetite-boosting hormone in male mice, but experts say it’s not yet clear whether the mechanism applies to humans.
GFP highlighting mouse neurons
Science Snapshot: How Brains Handle Surprise Parties
Lisa Winter | Jun 3, 2022
When unexpected events occur, norepinephrine signals mouse brains to pay attention to key details.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
Pink rat pups piled on top of each other.
Rat Sperm Generated from Stem Cells
Alejandra Manjarrez | Apr 7, 2022
Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.
Image of brain cells showing pyramidal neurons in green, astrocytes in red, and microglia in blue
Replacing Microglia Treats Neurodegenerative Disease in Mice
Shawna Williams | Mar 17, 2022
Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.
Illustration of gray bacteriophages approaching and infecting a red and orange bacteria that has multiple fimbria protruding from it.
Bacteria-Infecting Viruses in Gut Microbiome Linked to Cognition
Dan Robitzski | Feb 16, 2022
Research in mice and flies suggests that bacteriophages, including those found in dairy foods, may have an influence on an animals’ ability to learn and remember information.
illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Sophie Fessl | Feb 11, 2022
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
white mouse with pups
Doubts Raised Over Whether Mice Can Truly Inherit Immunity
David Adam | Jan 26, 2022
An independent lab fails to replicate results suggesting mammals exposed to pathogens could pass on immunological protections through epigenetic mechanisms.
white mouse running on a light blue wheel
Tinkering with Gut Microbes Boosts Brain Plasticity in Mice
Sophie Fessl | Jan 13, 2022
Intestinal bacteria contribute to the effect of stimulating environments on the brain’s ability to adapt, a study concludes.
Neuro collage
Our Favorite Neuroscience Stories of 2021
Chloe Tenn | Dec 29, 2021
From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.
grey and purple cancer cells under a microscope
Cell Diversity Could Spell Trouble for Animal Models of Cancer
David Adam | Nov 19, 2021
Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.  
A grid of images showing different cross sections of a human brain MRI.
Study Links Flu to Increased Parkinson’s Risk a Decade Later
Dan Robitzski | Nov 19, 2021
Epidemiological research suggests that a flu diagnosis might be one factor in the eventual onset of the neurodegenerative disease, but experts say it doesn’t prove a causal relationship.
Rounded red and green fluorescent cells are visible on a light and dark gray background
Neurons Firing Together Generate Spontaneous Pain
Abby Olena | Nov 10, 2021
Abnormal sympathetic neuron growth leads to simultaneous activation of clusters of sensory neurons, causing the difficult-to-treat sensation.