Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice
The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.
Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

mice
Australian Research Faces Impending Scarcity of Lab Rodents
Australian Research Faces Impending Scarcity of Lab Rodents
Bianca Nogrady | Jul 20, 2021
The Australian biomedical research community is stunned by the announced wind-down of the country’s biggest supplier of mice and rats.
Mice Plague Eastern Australia in Record Numbers
Mice Plague Eastern Australia in Record Numbers
Bianca Nogrady | Jul 12, 2021
A population explosion that began late last year has yet to abate. Meanwhile, researchers are exploring novel approaches to combat the nonnative species.
Microscopic Robots Deliver Drugs to the Brain
Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
Lab-Grown Mouse Embryos Form Limbs and Organs
Lab-Grown Mouse Embryos Form Limbs and Organs
Lisa Winter | Mar 19, 2021
The embryos completed one-third of their total gestation outside of a uterus.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
A Simple Genetic Change Adds Limb-Like Bones to Zebrafish Fins
A Simple Genetic Change Adds Limb-Like Bones to Zebrafish Fins
Abby Olena | Feb 5, 2021
A gain-of-function mutation in a single gene reveals ancient limb-forming capacity that has been preserved for hundreds of millions of years.
A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena | Jan 20, 2021
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Astrocytes, Not Just Neurons, Play a Role in Sleep
Astrocytes, Not Just Neurons, Play a Role in Sleep
Abby Olena | Sep 24, 2020
In mice, the brain’s main glial cell type exhibits distinctive patterns of activity across the sleep-wake cycle and influences the response to sleep deprivation.
Deep Brain Optogenetic Control Without Implants
Deep Brain Optogenetic Control Without Implants
Ruth Williams | Apr 30, 2020
Engineering an ultra-sensitive light-activated ion channel into brain cells allows for the control of neurons in live animals without a brain-implanted light source.
Infographic: Exercise’s Anticancer Mechanisms
Infographic: Exercise’s Anticancer Mechanisms
Bente Klarlund Pedersen | Apr 1, 2020
A look at the molecular processes that may feed into the tumor-fighting effects of physical activity
Infographic: CRISPR’d Cancer
Infographic: CRISPR’d Cancer
Rachael Moeller Gorman | Apr 1, 2020
Researchers use a new way to deliver CRISPR/Cas9 to tumors in mice, wiping out the cancer.
Artificial Intelligence Discovers Potent Antibiotic
Artificial Intelligence Discovers Potent Antibiotic
Amy Schleunes | Feb 22, 2020
Researchers used a machine-learning platform to test more than 100 million molecules for antibacterial activity.
Former Jackson Lab Director Ken Paigen Dies
Former Jackson Lab Director Ken Paigen Dies
Shawna Williams | Feb 20, 2020
The geneticist’s long career included leading the laboratory’s recovery from a devastating 1989 fire.
Image of the Day: Synchronized Neurons
Image of the Day: Synchronized Neurons
Amy Schleunes | Feb 14, 2020
Memory formation in mice involves coordinated activity at the cellular level that likely leads to new circuits in the brain.
Snake Venom Gland Organoids Produce Functional Toxins
Snake Venom Gland Organoids Produce Functional Toxins
Amy Schleunes | Jan 24, 2020
Stem cells from nine snake species respond to tissue culturing techniques previously used only on mouse and human stem cells.
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Emma Yasinski | Dec 7, 2019
Altering DNA methylation in a particular area of the hypothalamus halved the animals’ voluntary exercise as adults.
Keto Diet Protects Mice from Flu
Keto Diet Protects Mice from Flu
Abby Olena | Nov 15, 2019
The low-carb, high-fat diet increases the presence of gamma-delta T cells in the animals’ lungs, improving a mucus barrier against the virus.
Long-Lived Neural Stem Cells Identified in Living Mice
Long-Lived Neural Stem Cells Identified in Living Mice
Ashley Yeager | Oct 22, 2019
New, unpublished results show some of the cells produce new neurons for up to 90 days, much longer than a previously identified set of neural stem cells that only generate neurons for a month or two.
EPA Aims to Drastically Reduce Animal Testing
EPA Aims to Drastically Reduce Animal Testing
Emily Makowski | Sep 11, 2019
The agency plans to stop funding virtually all toxicology studies in mammals by 2035.