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| 10+ min read
The myriad species floating atop the world’s seas, called neuston, are mysterious and understudied, complicating efforts to clean up plastic pollution.

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<em>Chlamydia</em> invades a host cell, forms a membrane-bound vacuole, or inclusion, and then modifies the protein composition of the structure&rsquo;s membrane. If immune cells detect <em>Chlamydia</em> before it forms the inclusion, they trigger T cells to produce interferon-&gamma; (IFN-&gamma;), a powerful cytokine. IFN-&gamma; activates the protein mysterin (also called RFN213), which attaches ubiquitin to the inclusion membrane, signaling the cell to destroy the inclusion&rsquo;s contents by dumping them into a lysosome (left). C. trachomatis produces GarD, a protein that integrates into the inclusion membrane itself and somehow prevents mysterin from attaching ubiquitin, allowing the bacterium to evade immune destruction while continuing to multiply and eventually bursting from the cell (right).

Infographic: How Chlamydia Evades Immune Detection

Magenta (DNA) and green (lysosome) fluorescent markers indicate that cells eject waste products from the cell before late mitosis.

Science Snapshot: Mitotic Housekeeping

Infographic showing endogenous adenosine enzymes acting on RNA (ADARs) edit genetic material in the cell by attaching to naturally occurring double-stranded RNAs, including mRNAs, and switching out A bases with I bases (left). Therapeutic RNA editing platforms based on this mechanism fall into one of two categories: either they use engineered enzymes, which generally consist of the editing part of the ADAR enzyme attached to another protein such as Cas13 that boosts specificity, alongside a guide RNA that targets the enzyme to the desired location (middle); or they consist of a guide RNA alone, which recruits an endogenous ADAR to edit the target sequence (right).

Infographic: RNA Editing Approaches

Infographic: How Pregnancy Changes Fat Tissue

An Australian water beetle walks on the underside of the water's surface.

Australian Beetles Walk on the Underside of Water’s Surface

Infographic: How Scientists Are Creating Coral Cell Lines

Ten Minute Sabbatical

illustration of how slow-growing and fast-growing fungi grow through a narrow channel

Infographic: How Fungi Squeeze Through Tight Spaces—or Don’t

View of Brandon Taylor's face during the book club discussion for Real Life.

Book Club Discussion of Brandon Taylor’s Real Life

Infographic: How to Ferret Out SARS-CoV-2 in Sewage

Book Club Discussion of Lulu Miller's Why Fish Don't Exist

Tour the Applewhite Lab

Infographic: Envisioning Macrophages

Certain Color Varieties of a Coral Are More Protected from Bleaching

Thousands of Sea Turtles Immobilized by Brutal Texas Winter Storm

See Pigs Master a Joystick Video Game

Conch Horn Finds Its Song Again After 17,000 Years

Coral Restorers

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Photo of a woman with straight dark hair looking fatigued lying in bed with a grey blanket covering her.

Immune Markers Help Identify Subgroups of ME/CFS Patients

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A watercolor illustration of the human brain.

New Neurons Continue to Form in Adult Human Brains

Image of salmon and tuna nigiri as well as California rolls arranged on a circular black plate.

Engineered Bacteria Detox Mercury from a Fish-Rich Diet

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A large number of stylized antibodies

The Holy Grail Hunt in De Novo Antibody Design

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Conceptual 3D image of a multicolored membrane protein on a black background.

Making the Most of Membrane Protein Production

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July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

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Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

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Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

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An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

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Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

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Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

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Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

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BRANDTECH Scientific Launches New Website for VACUU·LAN® Lab Vacuum Systems