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How Does the Placebo Effect Work?
Placebo analgesia might be all in the head, but that doesn’t mean it’s not real.
How Does the Placebo Effect Work?
How Does the Placebo Effect Work?

Placebo analgesia might be all in the head, but that doesn’t mean it’s not real.

Placebo analgesia might be all in the head, but that doesn’t mean it’s not real.

placebo

A conceptual 3D illustration of motor neurons degrading
Canada Approves Experimental ALS Therapy
Andy Carstens | Jun 14, 2022 | 3 min read
The country’s provisional go-ahead could increase pressure already being exerted on the US Food and Drug Administration to approve the therapy.
line of people waiting outside mass vaccination site
“Nocebo” Effect May Cause Majority of COVID-19 Vaccine Symptoms
Natalia Mesa, PhD | Jan 18, 2022 | 2 min read
A negative version of the placebo effect may be behind many instances of mild side effects associated with the jabs, a study suggests.
Capsule Reviews
Bob Grant | Aug 1, 2014 | 3 min read
The Myth of Mirror Neurons, Curious, Shadow Medicine, and Doctored
Placebo’s Double Whammy
Kerry Grens | Oct 14, 2013 | 2 min read
Sham treatments can both reduce pain and increase pleasure, and do so affecting similar circuitry in the brain.
Worried Sick
Megan Scudellari | Jul 1, 2013 | 10+ min read
Expectations can make you ill. Fear can make you fragile. Understanding the nocebo effect may help prevent this painful phenomenon.
Rats Get Placebo Effect
Dan Cossins | Nov 28, 2012 | 1 min read
Rodents experience placebo-induced pain relief, providing a new model with which to investigate the phenomenon.
Personality Predicts Placebo Effect
Dan Cossins | Nov 16, 2012 | 3 min read
People with certain personality traits are more likely to get pain relief from a placebo, a finding that could help improve clinical trials.
A Placebo for Schizophrenia?
Cristina Luiggi | Jun 25, 2012 | 1 min read
The placebo effect in clinical trials of the mental disorder has increased over the past decade.
Placebos Use Pot Receptor
Tia Ghose | Oct 5, 2011 | 1 min read
Some pain-relief placebos work in part by activating a cannabinoid receptor, stimulating the same pathway as marijuana.
Placebo of HIV Trials
Jef Akst | Jul 14, 2011 | 1 min read
A new study confirms that a “trial effect”—in which patients improve simply as a result of taking part in a drug study—once existed among HIV trial participants.
Puzzle Me This
Graeme Stemp-Morlock | Jan 31, 2011 | 3 min read
What substance is supposed to have no effect but can make people feel better, has no chance for a big monetary payoff but is worth billions, and is used in virtually every rigorous clinical trial but has no single, universal formulation? 
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