Applications for Phase 1 and 2 human studies in Germany frequently lack sufficient information about an intervention’s efficacy in animal experiments, according to a new study.  

Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.

The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.

Researchers overestimate the reliability of findings from animal studies that are part of the Reproducibility Project: Cancer Biology.

Animal experiments published in a handful of cardiovascular journals mostly ignore NIH guidelines.

Scientists shut down cancer-causing fusion genes with CRISPR.

At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.