Forced-Swim Test Criticized as Uninformative, Cruel
Forced-Swim Test Criticized as Uninformative, Cruel
Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.
Forced-Swim Test Criticized as Uninformative, Cruel
Forced-Swim Test Criticized as Uninformative, Cruel

Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.

Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.

preclinical
Stem Cell Funding Agency CIRM Is Nearly Out of Funds
Stem Cell Funding Agency CIRM Is Nearly Out of Funds
Chia-Yi Hou | Jul 8, 2019
The California Institute for Regenerative Medicine has been funding research since it formed in 2004, giving out nearly $3 billion in grants to date.
CRISPR Treatment for Duchenne Muscular Dystrophy Helps Dogs
CRISPR Treatment for Duchenne Muscular Dystrophy Helps Dogs
Catherine Offord | Aug 31, 2018
Researchers boosted levels of the dystrophin protein to nearly normal levels in a canine model of the disease.
Shoddy Preclinical Data Used in Clinical Trial Proposals
Shoddy Preclinical Data Used in Clinical Trial Proposals
Kerry Grens | Apr 5, 2018
Applications for Phase 1 and 2 human studies in Germany frequently lack sufficient information about an intervention’s efficacy in animal experiments, according to a new study.  
Want to Boost Reproducibility? Get Another Lab Involved
Want to Boost Reproducibility? Get Another Lab Involved
Jim Daley | Feb 22, 2018
Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.
Investigation Questions Transparency for Failed TB Vax
Investigation Questions Transparency for Failed TB Vax
Jef Akst | Jan 11, 2018
The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
Catherine Offord | Oct 3, 2017
Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Abby Olena | Aug 30, 2017
Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.
Preclinical Cancer Studies Not as Reproducible as Thought
Preclinical Cancer Studies Not as Reproducible as Thought
Jef Akst | Jun 30, 2017
Researchers overestimate the reliability of findings from animal studies that are part of the Reproducibility Project: Cancer Biology.
Preclinical Studies Don't Regularly Adhere to Best Practices
Preclinical Studies Don't Regularly Adhere to Best Practices
Kerry Grens | May 8, 2017
Animal experiments published in a handful of cardiovascular journals mostly ignore NIH guidelines.