An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
ABOVE: © LISA CLARK
Infographic: Modeling Neurodegenerative Diseases with Yeast
Infographic: Modeling Neurodegenerative Diseases with Yeast

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

ABOVE: © LISA CLARK

proteasome

Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
young man vaping
Scientists Study Vaping’s Harm as Second Death Reported
Nicoletta Lanese | Sep 5, 2019
In light of recent reports of electronic-cigarette–related illness and death, UNC Chapel Hill professor Robert Tarran discusses the dangerous effects of e-liquids on the lungs.
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Pioneering Research in E3 Ubiquitin Ligase Biology and Applications to Drug Discovery
The Scientist Creative Services Team in collaboration with Bio-Techne | Sep 15, 2021
Jennifer Johnston discusses how a better understanding of ubiquitin-proteasome system elements can potentially aid neurodegenerative disease therapeutics.
Contributors
Diana Kwon | May 1, 2017
Meet some of the people featured in the May 2017 issue of The Scientist.
Infographic: Proteasome Basics
John Hines and Craig M. Crews | Apr 30, 2017
The structure and function of the cell's protein-degrading machine
Forced Feeding
Edyta Zielinska | Feb 1, 2012
Editor's choice in drug development
Death or Damage of Dopamine Neurons
Bobby Thomas and M. Flint Beal | Feb 1, 2011
The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. 
The Genes of Parkinson’s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.