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Advanced diagnostic testing methods empower scientists to swiftly and precisely detect STIs. 

sexually transmitted diseases

A cluster of spiral-shaped Treponema pallidum bacteria, the causative agent of syphilis.

Science Falls Behind as Syphilis Stages Another Comeback

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How Chlamydia Guards Itself Against the Immune System

<em>Chlamydia</em> invades a host cell, forms a membrane-bound vacuole, or inclusion, and then modifies the protein composition of the structure&rsquo;s membrane. If immune cells detect <em>Chlamydia</em> before it forms the inclusion, they trigger T cells to produce interferon-&gamma; (IFN-&gamma;), a powerful cytokine. IFN-&gamma; activates the protein mysterin (also called RFN213), which attaches ubiquitin to the inclusion membrane, signaling the cell to destroy the inclusion&rsquo;s contents by dumping them into a lysosome (left). C. trachomatis produces GarD, a protein that integrates into the inclusion membrane itself and somehow prevents mysterin from attaching ubiquitin, allowing the bacterium to evade immune destruction while continuing to multiply and eventually bursting from the cell (right).

Infographic: How Chlamydia Evades Immune Detection

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Obesity Protects Against Genital Herpes in Mice, Study Finds

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Opinion: Manuscripts and Art Support Archaeological Evidence that Syphilis Was in Europe Long Before Explorers Could Have Brought It Home from the Americas

Julius Schachter, Renowned Chlamydia Researcher, Dies at 84

Health Officials Agree Undetectable HIV Levels Likely Mean Uninfectious

Meningitis Vaccine May Protect Against Gonorrhea

Untreatable Gonorrhea Rising Globally

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What Happens When a Fly Lands on Your Food? 

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Universe 25 Experiment

Image of an infant’s feet that are visible in a hospital incubator.

Record-Breaking DNA Sequencing Technology Could Transform Newborn Care

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Impersonation Scandals Shake Academic Publishing

Multimedia

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

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Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

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Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

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OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel