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CAR Macrophages Tackle Challenges in Solid Cancer Treatment
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
solid cancer
Armored CAR T Cells Break Through Immune Suppression in Solid Tumors
Jennifer Zieba, PhD | Sep 26, 2022 | 3 min read
Researchers determined the safety and antitumor ability of genetically engineered CAR T cells that circumvent immune suppression in a prostate cancer phase I clinical trial.
Finding CAR T Cells in Solid Tumors at Single-Cell Resolution
The Scientist Creative Services Team in collaboration with Miltenyi Biotec | Nov 12, 2021 | 1 min read
Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM).
Advances in Solid Tumor Immunotherapies
Sartorius | Oct 6, 2021 | 1 min read
By screening for novel tumor targets, researchers build better CAR-T cell therapies.
Enhancing the Efficacy of CAR-T Cell Therapies
The Scientist Creative Services Team in Collaboration with IsoPlexis | Jun 29, 2021 | 1 min read
Jessica Morris will discuss strategies to improve CAR-T cell targeting, activation, and killing capabilities.
COVID-19 More Deadly with Blood than Solid Cancer: Study
Marcus A. Banks | Feb 16, 2021 | 4 min read
Death rates among blood cancer patients who contract COVID-19 are higher than for those with other cancers, pointing to impaired immunity that makes it hard to overcome the virus.
Immunotherapy Combo Reduces Solid Tumors in Mice
Amanda Heidt | Sep 9, 2020 | 5 min read
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.