ADVERTISEMENT
ADVERTISEMENT
Michael Green in the lab, smiling at the camera
Molecular Biologist Michael Green Dies at 69
Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 
Molecular Biologist Michael Green Dies at 69
Molecular Biologist Michael Green Dies at 69

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 

splicing

Microscopy image of blue stained cohesin proteins.
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Shafaq Zia | Mar 3, 2023 | 2 min read
Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 
A photograph of Christine Guthrie and Hiten Madhani
RNA Pioneer Christine Guthrie Dies at 77
Amanda Heidt | Sep 1, 2022 | 5 min read
Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.
SARS-CoV-2 Disables Key Components of Human Cells’ Defense System
Catherine Offord | Oct 22, 2020 | 4 min read
Researchers detail how viral proteins interact with host RNA to disrupt the cell’s ability to fight back against infection.
Infographic: How Splicing of Genes Can Affect Heart Health
Gabrielle M. Gentile, Hannah J. Wiedner, Emma R. Hinkle, and Jimena Giudice | Jan 13, 2020 | 2 min read
The way in which mRNA transcripts are cut can influence the elasticity of the organ.
a pair of scissors cuts a film strip that's curled into a helix
Alternative Splicing Provides a Broad Menu of Proteins for Cells
Gabrielle M. Gentile, Hannah J. Wiedner, Emma R. Hinkle, and Jimena Giudice | Jan 13, 2020 | 10+ min read
It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.
Tau Linked to RNA Splicing Errors in Flies
Emily Makowski | Oct 8, 2019 | 2 min read
In brain samples from people with Alzheimer’s disease, the protein aggregates more strongly bound proteins involved in processing RNA, the same study finds.
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Catherine Offord | Jul 26, 2019 | 1 min read
A trial is recruiting patients to test the gene-editing technology’s ability to treat an inherited form of blindness caused by a mutation in the CEP290 gene.
A New Role for Yeast Introns: Helping Cells Cope Under Stress
Katarina Zimmer | Jan 16, 2019 | 4 min read
Two studies contest the idea that the noncoding sequences are just “junk DNA,” demonstrating that they play important roles in the regulation of cell growth.
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Catherine Offord | Oct 18, 2018 | 2 min read
This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.
the Lasker award trophy
Lasker Awards Recognize Work on Histones, Anesthesia, RNA
Shawna Williams | Sep 11, 2018 | 2 min read
This year’s winners are C. David Allis, Michael Grunstein, John Glen, and Joan Steitz.
Sex Reversal Mystery Explained?
Jef Akst | Jun 15, 2017 | 1 min read
A proposed mechanism for how bearded dragons with male chromosomes hatch as females at high temperatures
Angela Brooks: Splicing Specialist
Diana Kwon | Apr 1, 2017 | 3 min read
At the University of California, Santa Cruz, the researcher combs the cancer genome, looking for weaknesses.
Controlled Splicing Extends Life Span in Roundworms
Ruth Williams | Dec 6, 2016 | 3 min read
Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 
ADVERTISEMENT