Purple 3D wireframe illustration of a brain in front of a vertical strand of DNA on a black background.

| 3 min read

Deceased and Live Brains Modify RNA and Express Protein Differently

Brains of the living and deceased have differences in RNA splicing and protein usage, introducing questions about how well the postmortem brain reflects the living organ.

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Event Date:

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Illustration of a blue piece of DNA with a red segment in its middle on a purple background. Blue and red segments that have been cut out surround the larger strand.

| 2 min read

Splicing Fungal Genes Help Cells Change Shape

splicing

An illustration of a perforated grey nucleus holding colorful spaghetti-like DNA strands.

Gene Proximity to Nuclear Speckles Drives Efficient mRNA Splicing

Karen Kelley Perkins, PhD | | 4 min read

Michael Green smiling at the camera in front of a shelf in the lab

Molecular Biologist Michael Green Dies at 69

Lisa Winter | | 2 min read

Microscopy image of blue stained cohesin proteins.

Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer

Shafaq Zia | | 2 min read

A photograph of Christine Guthrie and Hiten Madhani

RNA Pioneer Christine Guthrie Dies at 77

Amanda Heidt | | 5 min read

SARS-CoV-2 Disables Key Components of Human Cells’ Defense System

Catherine Offord | | 4 min read

Infographic: How Splicing of Genes Can Affect Heart Health

Gabrielle M. Gentile,Hannah J. Wiedner,Emma R. HinkleandJimena Giudice | | 6 min read

a pair of scissors cuts a film strip that's curled into a helix

Alternative Splicing Provides a Broad Menu of Proteins for Cells

Gabrielle M. Gentile,Hannah J. Wiedner,Emma R. HinkleandJimena Giudice | | 10+ min read

Tau Linked to RNA Splicing Errors in Flies

Emily Makowski | | 2 min read

Researchers Launch First Study of In Vivo CRISPR Therapy in Humans

Catherine Offord | | 1 min read

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Trending

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The Biggest Breakthroughs in Cell Biology in 2025

From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

Gollum, the extremely territorial character from The Lord of the Rings, famous for his line, “My precious,” sits on a rock, looking up.

The Gollum Effect: 44 Percent of Scientists Report Territorial Research Experiences

Survey data showed that hoarding research topics and resources, termed the Gollum effect, has a lasting impact on trainees and perpetuates a toxic research culture.

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Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

person doing the finger prick test for measuring blood glucose. A new noninvasive method could provide an alternative to such invasive blood tests.

Measuring Blood Sugar Without Painful Pricks? A New Test Scans Skin

Shining near-infrared light on a person’s skin helped scientists accurately track his blood glucose levels, offering a potential noninvasive way to monitor diabetes.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

In this webinar, Jesús Tintos-Hernandez, Setsu Endoh-Yamagami, and Amaris Castañon will discuss the latest advances and innovations in neuroscience disease cell models.

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Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services