Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
ABOVE: MODIFIED FROM © ISTOCK.COM, DR_MICROBE
How Chaos in Chromosomes Helps Drive Cancer Spread
How Chaos in Chromosomes Helps Drive Cancer Spread

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

ABOVE: MODIFIED FROM © ISTOCK.COM, DR_MICROBE

STING

Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Catherine Offord | Jan 24, 2020
This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.