As a deadly smallpox outbreak ravaged Boston, one of the city’s leaders advocated for a preventive measure he’d learned about from Onesimus, an enslaved man.

Last year humanity confronted our biggest challenge in a century. Science helped us see the light at the end of the tunnel. But we need to keep moving forward to emerge.

Take a break from the bench to puzzle and peruse.

Half a year after infection, people who had recovered from COVID-19 had robust antibodies, along with traces of the virus in their gut, which may drive long-lasting immunity.

The results mark the second experimental COVID-19 vaccine to show high efficacy, but the study is not complete and the data have not been peer reviewed.

Vaccine experts say the results surpass their expectations, but the study is not complete, and the data have not been peer reviewed.

Meet some of the people featured in the November 2020 issue of The Scientist.

A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.

As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.