Man in personal protective equipment (glasses, gloves, cap, and coat) watching plants go through a piece of machinery.
Canada Approves World’s First Plant-Based COVID-19 Vaccine
Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.
ABOVE: Medicago
Canada Approves World’s First Plant-Based COVID-19 Vaccine
Canada Approves World’s First Plant-Based COVID-19 Vaccine

Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.

Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.

ABOVE: Medicago

vaccine design

Two vaccine syringes on a baggy labelled with San Diego Zoo and Bonobo
The Rise of COVID-19 Vaccines for Animals
Chris Baraniuk | Dec 9, 2021
Thousands of animals have had their shot already. How many more really need it?
close-up of a mosquito on human skin
Hope, Concern Surround WHO Green Light of First Malaria Vaccine
Katarina Zimmer | Oct 28, 2021
RTS,S has several flaws but could still save tens of thousands of lives, experts say.
moderna and pfizer vaccine vials
Moderna vs. Pfizer: Is There a “Best” mRNA Vaccine?
Alejandra Manjarrez | Sep 24, 2021
Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna’s elicits a stronger immune response and might be better at preventing breakthrough infections.  
Updated Mar 8
A healthcare worker holds up three syringes with clear medicine
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.
rice plants growing in a room with metal walls under artificial light
Rice-based Cholera Vaccine Induces Antibodies in Small Trial
Alejandra Manjarrez | Jul 8, 2021
Immune-response levels to the edible vaccine varied among the subjects, possibly due to differences in the gut microbiome.
Illustration of the BCG vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
close-up of empty vaccine vials in a factory
The Quest for a Universal Coronavirus Vaccine
Diana Kwon | Jun 29, 2021
Scientists are on the hunt for a shot that will protect against not only SARS-CoV-2, but other members of its family that may emerge in the future.
Mucosal Vaccines Protect Mice from Viruses, Cancer
Emma Yasinski | Jun 1, 2021
Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.
Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
Ruth Williams | May 12, 2021
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
Pharma, US Government Plan for COVID-19 Booster Shots
Jef Akst | Apr 16, 2021
It’s unclear how long protections against infection will last from the initial vaccinations, and health authorities say additional jabs will likely be necessary.
COVID-19, SARS-CoV-2, coronavirus, pandemic, vaccine, vaccine trials, combination, mix and match, immunity, antibodies, T cells, Pfizer, Moderna, AstraZeneca, clinical trials
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
COVID-19, SARS-CoV-2, coronavirus, pandemic, pseudovirus, chimeric virus, disease & medicine, techniques, HIV, VSV, vaccine, variants, mutations
What Pseudoviruses Bring to the Study of SARS-CoV-2
Amanda Heidt | Feb 16, 2021
Engineered viruses that don’t replicate provide a tractable model for scientists to safely study SARS-CoV-2, including research into vaccine efficacy and emerging variants.
Vaccines Versus the Mutants
Anthony King | Feb 8, 2021
Facing new variants of SARS-CoV-2, some vaccines may offer more robust protection or be more easily redesigned to target them.
SARS-CoV-2, COVID-19, coronavirus, pandemic, virus, vaccine, vaccination, outbreak, infectious disease, Johnson & Johnson, Moderna, Pfizer, drug development
One-Shot COVID-19 Vaccine Prevents Severe Disease
Asher Jones | Jan 29, 2021
Johnson & Johnson’s vaccine is less effective at preventing COVID-19 than other approved vaccines are, but experts say it could still be an important tool in curbing the pandemic.
mrna vaccine covid-19 astrazeneca pfizer biontech moderna coronavirus pandemic sars-cov-2 spike protein
The Promise of mRNA Vaccines
Diana Kwon | Nov 25, 2020
Long before Moderna’s and Pfizer’s COVID-19 shots, scientists had been considering the use of genetically encoded vaccines in the fight against infectious diseases, cancer, and more.
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
How Some Vaccines Protect Against More than Their Targets
Shawna Williams | Nov 1, 2020
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
COVID-19, SARS-CoV-2, pandemic, coronavirus, clinical trials, safety, vaccine, Johnson & Johnson, Janssen
Johnson & Johnson Pauses COVID-19 Vaccine Trials
Amanda Heidt | Oct 13, 2020
The company voluntarily paused its studies, including one in Phase 3, after an unexplained illness in a patient.