A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.
Slow Vaccine Delivery May Maximize Immune Response
Slow Vaccine Delivery May Maximize Immune Response

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.

vaccine design
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez | Sep 15, 2022
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
commercial airplane<br><br>
Air France Announces End to Research Monkey Transport
Andy Carstens | Jul 6, 2022
The shift is likely to add to an ongoing shortage of primates used in labs, which could slow progress in future COVID-19 vaccine development and other areas.
iStock
The Scientist Speaks - To Conserve and Protect: The Quest for Universal Vaccines
Niki Spahich, PhD
Patrick Wilson discusses the challenges in designing universal vaccines and his work developing one for influenza.
Vaccine illustration&nbsp;
Infographic: Inducing Active Immunity Against Opioid Overdose
Tori Rodriguez | Jun 13, 2022
How scientists aim to induce an immune response against addictive drugs
Illustration of a syringe with a person falling out of a bottle of pills
Opioid Vaccines as a Tool to Stem Overdose Deaths
Tori Rodriguez | Jun 13, 2022
Researchers are turning to the immune system for help in treating addiction and preventing overdose.
Spraying spray bottle
Nasal Vaccines Are Commercially High Risk, Perhaps High Reward
Jef Akst | Jun 13, 2022
Dozens of intranasally delivered vaccines targeting SARS-CoV-2 are in development. Could they pave the way for widespread nasal vaccination in the future?
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano | Jun 1, 2022
The results could help guide the design of new vaccines for the disease.
Man in personal protective equipment (glasses, gloves, cap, and coat) watching plants go through a piece of machinery.
Canada Approves World’s First Plant-Based COVID-19 Vaccine
Natalia Mesa | Feb 25, 2022
Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.
Two vaccine syringes on a baggy labelled with San Diego Zoo and Bonobo
The Rise of COVID-19 Vaccines for Animals
Chris Baraniuk | Dec 9, 2021
Thousands of animals have had their shot already. How many more really need it?
close-up of a mosquito on human skin
Hope, Concern Surround WHO Green Light of First Malaria Vaccine
Katarina Zimmer | Oct 28, 2021
RTS,S has several flaws but could still save tens of thousands of lives, experts say.
moderna and pfizer vaccine vials
Moderna vs. Pfizer: Is There a “Best” mRNA Vaccine?
Alejandra Manjarrez | Sep 24, 2021
Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna’s elicits a stronger immune response and might be better at preventing breakthrough infections.  
Updated Mar 8
A healthcare worker holds up three syringes with clear medicine
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.
rice plants growing in a room with metal walls under artificial light
Rice-based Cholera Vaccine Induces Antibodies in Small Trial
Alejandra Manjarrez | Jul 8, 2021
Immune-response levels to the edible vaccine varied among the subjects, possibly due to differences in the gut microbiome.
Illustration of the BCG vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
close-up of empty vaccine vials in a factory
The Quest for a Universal Coronavirus Vaccine
Diana Kwon | Jun 29, 2021
Scientists are on the hunt for a shot that will protect against not only SARS-CoV-2, but other members of its family that may emerge in the future.
Mucosal Vaccines Protect Mice from Viruses, Cancer
Emma Yasinski | Jun 1, 2021
Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.
Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
Ruth Williams | May 12, 2021
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
Pharma, US Government Plan for COVID-19 Booster Shots
Jef Akst | Apr 16, 2021
It’s unclear how long protections against infection will last from the initial vaccinations, and health authorities say additional jabs will likely be necessary.