T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

vaccine design
Pharma, US Government Plan for COVID-19 Booster Shots
Pharma, US Government Plan for COVID-19 Booster Shots
Jef Akst | Apr 16, 2021
It’s unclear how long protections against infection will last from the initial vaccinations, and health authorities say additional jabs will likely be necessary.
COVID-19 Vaccine Combos Aim to Boost Immunity
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
What Pseudoviruses Bring to the Study of SARS-CoV-2
What Pseudoviruses Bring to the Study of SARS-CoV-2
Amanda Heidt | Feb 16, 2021
Engineered viruses that don’t replicate provide a tractable model for scientists to safely study SARS-CoV-2, including research into vaccine efficacy and emerging variants.
Vaccines Versus the Mutants
Vaccines Versus the Mutants
Anthony King | Feb 8, 2021
Facing new variants of SARS-CoV-2, some vaccines may offer more robust protection or be more easily redesigned to target them.
One-Shot COVID-19 Vaccine Prevents Severe Disease
One-Shot COVID-19 Vaccine Prevents Severe Disease
Asher Jones | Jan 29, 2021
Johnson & Johnson’s vaccine is less effective at preventing COVID-19 than other approved vaccines are, but experts say it could still be an important tool in curbing the pandemic.
The Promise of mRNA Vaccines
The Promise of mRNA Vaccines
Diana Kwon | Nov 25, 2020
Long before Moderna’s and Pfizer’s COVID-19 shots, scientists had been considering the use of genetically encoded vaccines in the fight against infectious diseases, cancer, and more.
Infographic: How Vaccines Train Innate Immunity
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
How Some Vaccines Protect Against More than Their Targets
How Some Vaccines Protect Against More than Their Targets
Shawna Williams | Nov 1, 2020
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
Johnson & Johnson Pauses COVID-19 Vaccine Trials
Johnson & Johnson Pauses COVID-19 Vaccine Trials
Amanda Heidt | Oct 13, 2020
The company voluntarily paused its studies, including one in Phase 3, after an unexplained illness in a patient.