Engineered viruses that don’t replicate provide a tractable model for scientists to safely study SARS-CoV-2, including research into vaccine efficacy and emerging variants.
Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.
DNA sequencing reveals that the virus responsible for the recent outbreak in the Americas originated in Brazil in 2014 and circulated undetected for months before the first cases were reported.