Omicron Propagates 70 Times Faster than Delta in Bronchi: Study

A preprint reports that the new SARS-CoV-2 variant multiplies faster in human bronchial tissue but slower in lung tissue than the Delta variant, potentially explaining how it’s spreading from person to person so quickly.

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An artist’s rendering of the Omicron variant portrays the virus as a lumpy blue sphere with several orange spike proteins jutting out of it.

An artist’s 3D rendering of the Omicron variant of SARS-CoV-2

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Newly shared preliminary data suggests that the Omicron variant of SARS-CoV-2 may target and infect tissues within the respiratory tract at different rates than do the Delta variant and other predecessors. In fact, some experts say, the Omicron variant may owe its enhanced transmissibility to its facility for infecting bronchial tissue far more than the lungs.

Findings from the research, which hasn’t yet undergone peer review, were shared online in a University of Hong Kong news release on Wednesday (December 15). In lung tissue taken from a human patient, the researchers found that the Omicron variant replicated roughly 70 times more in the bronchial tissue that makes up tubes leading into the lungs than did the Delta variant after 24 hours. However, Omicron variant replicated more than 10 times slower in lung tissue than the original coronavirus variant. It’s difficult to extrapolate clinical outcomes from this type of lab-based research, ...

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  • black and white image of young man in sunglasses with trees in background

    Dan Robitzski

    Dan is a News Editor at The Scientist. He writes and edits for the news desk and oversees the “The Literature” and “Modus Operandi” sections of the monthly TS Digest and quarterly print magazine. He has a background in neuroscience and earned his master's in science journalism at New York University.
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