Omicron Propagates 70 Times Faster than Delta in Bronchi: Study

A preprint reports that the new SARS-CoV-2 variant multiplies faster in human bronchial tissue but slower in lung tissue than the Delta variant, potentially explaining how it’s spreading from person to person so quickly.

Written byDan Robitzski
| 5 min read
An artist’s rendering of the Omicron variant portrays the virus as a lumpy blue sphere with several orange spike proteins jutting out of it.
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Newly shared preliminary data suggests that the Omicron variant of SARS-CoV-2 may target and infect tissues within the respiratory tract at different rates than do the Delta variant and other predecessors. In fact, some experts say, the Omicron variant may owe its enhanced transmissibility to its facility for infecting bronchial tissue far more than the lungs.

Findings from the research, which hasn’t yet undergone peer review, were shared online in a University of Hong Kong news release on Wednesday (December 15). In lung tissue taken from a human patient, the researchers found that the Omicron variant replicated roughly 70 times more in the bronchial tissue that makes up tubes leading into the lungs than did the Delta variant after 24 hours. However, Omicron variant replicated more than 10 times slower in lung tissue than the original coronavirus variant. It’s difficult to extrapolate clinical outcomes from this type of lab-based research, ...

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    Dan is an award-winning journalist based in Los Angeles who joined The Scientist as a reporter and editor in 2021. Ironically, Dan’s undergraduate degree and brief career in neuroscience inspired him to write about research rather than conduct it, culminating in him earning a master’s degree in science journalism from New York University in 2017. In 2018, an Undark feature Dan and colleagues began at NYU on a questionable drug approval decision at the FDA won first place in the student category of the Association of Health Care Journalists' Awards for Excellence in Health Care Journalism. Now, Dan writes and edits stories on all aspects of the life sciences for the online news desk, and he oversees the “The Literature” and “Modus Operandi” sections of the monthly TS Digest and quarterly print magazine. Read more of his work at danrobitzski.com.

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