Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.

| 2 min read

What’s the Difference Between Gene Knockdown and Gene Knockout?

There are many techniques that allow scientists to silence a gene, but whether the effect is transient or permanent depends on the type of approach.

Depiction of human DNA helix.

| 3 min read

An Epigenetic Strategy to Control Bad Cholesterol

Pruett-Miller in front of a computer with data graphs speaking with two people.

| 6 min read

All Roads Lead to Genome Editing

zinc finger nuclease

Illustration of DNA

Can “Gene Writing” Deliver What Gene Editing Can’t?

Dan Robitzski | | 10+ min read

Preliminary Results Point to Success of In Vivo Gene Editing

Carolyn Wilke | | 2 min read

Gene Editing Treats Mitochondrial Disorders in Mice

Catherine Offord | | 2 min read

Early Results of First In Vivo Gene-Editing Trial Encouraging

Kerry Grens | | 2 min read

Man Receives First In Vivo Gene-Editing Therapy

Kerry Grens | | 2 min read

First In Vivo Human Genome Editing to Be Tested in New Clinical Trial

Abby Olena, PhD | | 4 min read

Gene Editing: From Roots to Riches

Amanda B. Keener | | 5 min read

Rewritten in Blood

Ruth Williams | | 2 min read

Positive Developments on the HIV Front

Bob Grant | | 2 min read

Messing with HIV

Jef Akst | | 1 min read

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Avant-Garde Science

Mary Beth Aberlin | | 3 min read

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When Zinc Fingers Miss the Mark

Tia Ghose | | 3 min read

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Zinc Fingers Bear Fruit

Bob Grant | | 1 min read

Page 1 of 1 - 16 Total Items

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Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

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What are the Risks and Benefits of a Cold Plunge?

Cold-water immersion enthusiasts tout its benefits for their health and wellbeing, but is it backed by scientific evidence?

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Why Do Some Women Crave Chocolate Before Their Period?

A combination of hormones and neurotransmitter interactions contributes to sweet cravings during the premenstrual phase.

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Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

The mitochondrial genome can help researchers map ancestry and better understand the inheritance of mitochondrial diseases.

Multimedia

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Transform Omics Workflows with Scalable Cell Prep

Levitation-based cell enrichment streamlines workflows and enhances reproducibility.

Conceptual image of genomic analysis showing multicolored DNA base sequences depicted as the letters C, G, A, and T.

Accelerating Cancer Research Through Comprehensive Genomic Analysis

Learn how the latest technology helps researchers overcome cancer research challenges.

May digest 2025 cover

May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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TaqMan Probe & Assays: Unveil What's Possible Together

Fuel your research with our high-quality TaqMan™ Assays and probes. Experience unmatched performance, reliability, and detailed support tailored to your scientific needs. Click to explore our comprehensive coverage options now!

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

In this webinar, Andre Mueller will introduce Aunty, the latest tool that scientists use for rapid, high-resolution protein stability testing.

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.

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Making Real-Time PCR More Straightforward

Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.

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Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.

Latest AI software simplifies image analysis and speeds up insights for scientists

The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.

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Agilent BioTek Cytation C10 Confocal Imaging Reader

From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.