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Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.
| 2 min read
There are many techniques that allow scientists to silence a gene, but whether the effect is transient or permanent depends on the type of approach.

zinc finger nuclease

Illustration of DNA

Can “Gene Writing” Deliver What Gene Editing Can’t?

Preliminary Results Point to Success of In Vivo Gene Editing

Gene Editing Treats Mitochondrial Disorders in Mice

Early Results of First In Vivo Gene-Editing Trial Encouraging

Man Receives First In Vivo Gene-Editing Therapy

First In Vivo Human Genome Editing to Be Tested in New Clinical Trial

Gene Editing: From Roots to Riches

Rewritten in Blood

Positive Developments on the HIV Front

Trending

A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

A drawing of men and women holding boxes, resigning en mass from their jobs as editors.

Editors Mass Resign from Elsevier Journal After Editor-in-Chief Let Go

Image of a Diploptera punctata cockroach.

Cockroach Milk Proteins Churn Out an Ig Nobel Win

In the TS 40th Anniversary template, Sarkis Mazmanian smiles in a black and white headshot photo on the left. In a photo on the right, he stands in front of a large image of a cross-section of the brain. He wears a navy jacket, a white shirt, and glasses.

Then and Now: Sarkis Mazmanian Finds Gut-Brain Links to Parkinson’s Disease

Multimedia

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

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Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

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Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

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CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

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Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays