Human ArraysA 20th century scientist may have spent an entire career studying the function of a single protein, never imagining that one day it would be possible to study every human gene at once. This capability comes in the form of a microarray, a surface collection of immobilized genes that can be simultaneously examined with specialized equipment.1 Many current applications of arrays, also known as biochips, can be used in functional genomics as scientists seek characteristic patterns of gene expression in different physiopathological states or tissues. A step beyond this, genomic linkage analysis associates genetic markers with disease phenotypes. Arrays also can support massive high-throughput genomic screening, assessing single-base genome changes (single nucleotide polymorphisms, or SNPs) that underlie individual variations in drug response. With many potential applications and the approaching genome explosion, a host of commercial arrays and array tools have suddenly appeared. This article examines ...
The Array of Today
Human Arrays Human Arrays (continued) A 20th century scientist may have spent an entire career studying the function of a single protein, never imagining that one day it would be possible to study every human gene at once. This capability comes in the form of a microarray, a surface collection of immobilized genes that can be simultaneously examined with specialized equipment.1 Many current applications of arrays, also known as biochips, can be used in functional genomics as scientists seek ch
Written byJorge Cortese
| 10 min read
Register for free to listen to this article
Listen with Speechify
0:00
10:00
Interested in reading more?
Become a Member of
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Add The Scientist as a preferred Google source to see more of our trusted coverage.
Meet the Author
- This person does not yet have a bio.View Full Profile
Published In
