Analysis of the human transcriptome is often limited to annotated sequences. In the May 3 Science, Philipp Kapranov and colleagues at Affymetrix Inc., California provide evidence for many undiscovered transcribed sequences from human chromosomes 21 and 22 (Science 2002, 296:916-919).Most microarray transcriptome analysis is based on annotated exon sequences. Kapranov et al. took an empirical approach and constructed microarrays containing 25-mer oligonucleotides spaced uniformly every 35 base-pa
Analysis of the human transcriptome is often limited to annotated sequences. In the May 3
Most microarray transcriptome analysis is based on annotated exon sequences. Kapranov
The authors predict that there may be as much as an order of magnitude greater transcription than is implied by the current annotation, and suggest that this approach could lead to array-guided transcription maps and the discovery of an extensive 'hidden transcriptome' awaiting functional characterization.
A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.
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In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.
Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.
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A new thermocycler technology helps scientists optimize reactions with six different settable temperature zones for better control and linear gradients.
The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.
The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.
From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.
Sapio Release 25.4, introducing a new Biorepository Management solution, enhanced sample management capabilities, and platform-wide enhancements designed to streamline lab operations and support high-throughput research environments.
