Zika virus can remain in the cerebrospinal fluid and lymph nodes of rhesus monkeys long after any symptoms have dissipated, researchers at Harvard Medical School reported in Cell this week (April 27). “Up until now, everyone was focused on the acute [infection]—what happens when a person gets infected initially by a mosquito bite. But what this paper tells us is that maybe, two months down the line, symptoms could manifest from this later stage of virus replication in the central nervous system and other sites,” Andres Pekosz of the Johns Hopkins Bloomberg School of Public Health in Baltimore who was not involved in the research told The Scientist. “Right now, we may be missing some of the disease associated with infection because we’re not looking far enough down the path.”
Two groups of scientists have developed some of the most-advanced mini brains, or organoids, to date. The teams described their ...