Week in Review

Where Zika virus persists in monkeys; more-advanced mini brains; artificial womb supports fetal lambs for weeks; cancer mutations in stem cell lines; science marches around the globe

CRISPR patent ruling appealed; CRISPR-based nucleic acid test; an experimental gene therapy for Duchenne muscular dystrophy and a cell-based protocol for Parkinson’s disease show promise in mice

Virus triggers gluten intolerance in mice; UK bank offers clinic-ready hESC lines; researchers debate giant virus origins; cephalopods edit RNA; scientists screen noncoding genome with CRISPR

European Patent Office greenlights CRISPR patent; scientists reconsider a cancer drug target; NIH accepts preprints in grant applications; MERS drug developers test antibodies; experts weigh the risks and benefits of whole-exome sequencing for healthy people

What proposed budget cuts could mean for NIH; how astrocytes help control circadian behaviors in mice; how mutations confer virulence to vaccine-derived polio; why cancer risk is in part “random”

Moving toward a fully synthetic yeast genome; backing up environmental data; regulating appetite with osteoblast hormones; investigating electrosensory organs in fish; contemplating federal science budgets

Remembering Eugene Garfield; protecting citizens from their own genes; a suicide switch for stem cells; storing movies on DNA; sterilizing insects with Wolbachia

Science policy at AAAS; international marches for science; circadian clock and aging; neurons for both itching and pain; a conversation with Iraqi-American epidemiologist Wael Al-Delaimy; “waviness” in whale nerves

CRISPR patent decision; DNA database errors; science marches around the globe; more

Two potential Science Advisors to the President talk federal funding, climate change research, science marches, and more; a conversation with Iranian-American geneticist Pardis Sabeti; standards for teaching evolution in Texas could change; bioengineers debut a stomach acid–powered ingestible sensor; toward killing cancer with bacteria; ecDNA and tumor evolution

March for science debate; an RNA vaccine for Zika; responses to Trump’s immigration order; native habitat restoration; views from local March for Science organizers; artificial cells and the Turing test

Chimeric embryos, organs; restrictions on marijuana research; toward temperature-independent vaccine storage; broadly neutralizing antibodies show promise for HIV treatment, prevention; Trump’s first week in office affects scientists; final three WHO Director-General candidates selected

Preprint editors; why cancer studies are hard to replicate; predicting new protein structures; toward a virus-free polio vaccine; Obama’s science legacy; defending tenure

Assessing marijuana research; epigenetics and genetic ancestry; producing stem cells with extra-embryonic potential; aging-related changes in glial cell gene expression; plant-soil feedback

Preprints in grant applications; how hummingbirds sense movement while hovering; fibril formations and Alzheimer’s disease; NIH issues peanut allergy guidelines; a new organ?

More anti-CRISPRs; Neanderthal genes in modern humans; a major diabetes retraction; how a dinosaur species lost its teeth; interviews with PLOS and r/science

More CRISPR enzymes found; exome study reveals novel disease associations; Ebola vaccine success; pregnancy-related brain changes; Year in Review

Postdoc pay; managing privacy during a misconduct investigation; self-editing genetic barcodes; putting the breaks on CRISPR; screen reveals long noncoding RNA functions 

Anonymity prevails in PubPeer litigation; USPTO hears CRISPR IP arguments; critical incident reporting for preclinical research; brain waves and Alzheimer’s disease; Breakthrough Prizes

Souped up super-resolution microscopy; how diet affects host-microbiome communication in mice; Zika-associated microcephaly can present after birth; newly sequenced genomes