R. CAESAR ET AL./CELL METABOLISM The type of fat a mouse consumes can affect the animal’s gut microbiome and in turn spur inflammation in fat tissue, a team led by investigators at the University of Gothenburg in Sweden has found. The team’s results were published in Cell Metabolism this week (August 27).
“We know that fat itself can act as inflammatory inducers in certain immune cells, we can’t ignore that fact,” said Vanessa Leone, a postdoc studying host-microbe interactions at the University of Chicago who was not involved in the study. “It’s just that diet-induce microbes also play a role, and they together work to increase that inflammation even higher and make it even worse.”
“It will be important to confirm these findings in humans using long-term dietary interventions wherein food intake is carefully controlled,” Peter Turnbaugh, a professor of microbiology and immunology at the University of California, San Francisco, wrote in an email.
WIKIMEDIA, LOUISA HOWARDSome damaged cells get by with a little mitochondria from their friends. The process, called intercellular mitochondrial transfer, has been well-documented over the last 10 years. But why—and how—do damaged cells acquire these donor organelles?
