Week in Review: January 16–20

Preprint editors; why cancer studies are hard to replicate; predicting new protein structures; toward a virus-free polio vaccine; Obama’s science legacy; defending tenure

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Convincing authors of preprints to submit their work to major journals is no different than approaching a scientist about unpublished work that he or she has presented at a conference, according to Christopher “Casey” Brown, a geneticist at the University of Pennsylvania who is one of three “preprint editors” recently recruited by PLOS Genetics to solicit non-peer–reviewed manuscripts.

“Editors are paying very close attention—at a whole number of journals—to the preprint atmosphere,” Brown told The Scientist. “The role of editors is changing a bit, there is more interest in this sort of thing.”

Following on its investigation into the reproducibility of psychology experiments, the Center for Open Science has led an effort involving five papers published in eLife last week (January 19), which describe attempts to replicate certain cancer biology studies. Reproducing published results proved challenging, the team reported.

“This is an extremely important effort. Even though the published results ...

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