Scientists at Harvard University have devised a way to record molecular events in E. coli cells using a CRISPR/Cas system. “It’s the first demonstration of the ordered acquisition of intentionally introduced DNA sequences,” the University of California, Berkeley’s Adam Arkin, who was not involved in the study, told The Scientist.
One of the risks associated with mitochondrial replacement therapy (MRT) is that a mother’s mutant mitochondrial DNA (mtDNA) might still make it into the resulting “three-parent” embryo. Researchers at Newcastle University and the Wellcome Trust Centre for Mitochondrial Research and their colleagues have devised an approach that appears to reduce this risk. “It’s a very beautiful and carefully conducted study that has improved the pronuclear transfer technique,” said Dieter Egli of the New York Stem Cell Foundation and Columbia University who was not involved in the work.
Scientists have estimated that specimens from at least three individuals thought to belong ...
