When Big Science Fails To Deliver, Researchers Invent New Strategies

Harold Furth could see the hard times coming. Oil prices were dropping and, with them, the prospects for funding research into alternative energies such as fusion, his specialty. So, like others in his field during the early 1980s, the head of the Princeton Plasma Laboratory started promoting his program as good basic research, rather than as the pursuit of a working fusion reactor. Meanwhile, researchers in pursuit of a malaria vaccine had their own troubles. Serious scientific obstacles h

Written byChristopher Anderson
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Harold Furth could see the hard times coming. Oil prices were dropping and, with them, the prospects for funding research into alternative energies such as fusion, his specialty. So, like others in his field during the early 1980s, the head of the Princeton Plasma Laboratory started promoting his program as good basic research, rather than as the pursuit of a working fusion reactor.

Meanwhile, researchers in pursuit of a malaria vaccine had their own troubles. Serious scientific obstacles had emerged, and the field was dissolving in chaos. Faced with Draconian funding cuts in recent years, policymakers like biochemist Charles Chambers at the American Institute of Biological Sciences (AIBS) responded in a manner similar to Furth’s: Rather than emphasizing the prospects of a working vaccine in the foreseeable future, they began touting the value of their malaria studies to basic immunological research.

And throughout the last two decades, intelligence pioneer John ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Published In

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research