Cells In A New Light By combining the sensitivity of fluorescent dyes with optical systems that can detect colorful but low-intensity fluorescent light, researchers in many life sciences are able to peer inside cells and view fine detail as never before. With a fluorescent microscope, an investigator is now better able to study individual cells and image subcellular entities, such as organelles, proteins, microtubules, and chromosomes. Owing to advances in fluorescent microscopy techniques, researchers have the ability to study the intracellular dynamics of living cells, as such events occur in real time.

SEPARATES SIGNALS" Nikon's QuadFluor epifluorescence illuminator
"Within the last 15 years, fluorescence microscopy has developed into one of the most important techniques in cell biology," comments Eric Gruenstein, a professor of molecular genetics and biochemistry at the University of Cincinnati Medical School and president of Cincinnati-based Intracellular Imaging Inc. "Two relatively recent developments have pushed fluorescence microscopy to...

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