Yeast Don't Need Oxygen

Scientists discover that ancestors of the unicellular fungi can synthesize essential biomolecules with only trace levels of O2.

Written byBob Grant
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Yeast cell membrane visualized by some membrane proteins fused with RFP and GFP fluorescent markersWIKIMEDIA COMMONS, MASUR

Yeast cells are capable of synthesizing steroid molecules—the basic building blocks of the biological membranes that are essential to eukaryotic life—using only trace amounts of oxygen, according to a study published on the website of the Proceedings of the National Academy of Sciences this Monday (August 8).

Life began its 3.8-billion-year evolutionary journey when the Earth was largely devoid of oxygen. For eons, anaerobic organisms ruled the planet until photosynthetic, ancestral bacteria proliferated in the ancient seas and filled the atmosphere with the gas about 2.4 billion years ago, opening the door to aerobic life.

But fossils of ancestral yeast cells harboring ancient steroid molecules—of which oxygen is a key component—indicated that these aerobic organisms were around prior to this profusion of atmospheric oxygen. How ...

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Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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