Apiarium, 1625

Galileo’s improvements to the microscope led to the first published observations using such an instrument.

Written byKerry Grens
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

MICROSCOPY ON PAPER: The first published record of microscopic observations was printed in the book Apiarium in 1625 (above, lower). Although the authors, Italian naturalists Federico Cesi and Francesco Stelluti, described the anatomy of bees in their text, the first microscopy illustrations were published five years later in Stelluti’s book, Persio. The arrangement of the bees in his illustration (above, top) echo the trio of bees in the family crest of Maffeo Barbarini, also known as Pope Urban VIII. The scientists’ tribute to Barbarini is evident also in their descriptions of the bees as Urbanas (domestic) and Barbaras (rural). According to a 1970 translation of Apiarium by Clara Sue Kidwell, Cesi and Stelluti wrote: “You have distinguished Urban bees by their customs, virtue, worthiness and barbarian bees by their swarms, purity, and harmony in singing.”University of Michigan Library (Special Collections Library); Courtesy History of Science Collections, University of Oklahoma Libraries (inset)

Around the turn of the 17th century, humans’ narrow, mesoscale view of the world was undergoing a dramatic expansion. Not only was the telescope invented—allowing people for the first time to peer into space at distances we still find hard to fathom—but the microscope as well. And standing in the middle of all these technological advances was Galileo Galilei, remembered chiefly for his contributions to the former invention.

“Many people do not realize that Galileo was indirectly responsible for the first publication of observations made with a microscope,” says Kerry Magruder, the curator of the History of Science Collections at the University of Oklahoma. People often think of Robert Hooke’s famous sketch of a flea or Anton van Leeuwenhoek’s descriptions of cells as the first ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

    View Full Profile

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH