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A photo of a dish in which cells, which look like small dots, have been enlarged and stained to make them visible to the naked eye.
New Swelling Technique Makes Cells Visible to the Naked Eye
A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.
New Swelling Technique Makes Cells Visible to the Naked Eye
New Swelling Technique Makes Cells Visible to the Naked Eye

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

microscopy
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022
Caught on Camera
The Scientist Staff | Dec 12, 2022 | 4 min read
See some of the coolest images recently featured by The Scientist.
New insights reveal how herpesvirus infiltrates the nervous system.
Herpes Kidnaps Proteins to Take Up Residence in the Nervous System
Roni Dengler, PhD | 3 min read
The herpes virus hitches a ride to the nuclei of neurons from a surprising source.
slime mold spores
Science Snapshot: Breaking the Mold
Lisa Winter | Nov 3, 2022 | 1 min read
This image took 5th place at the 2022 Nikon Small World Photomicrography Competition.
Close up of spider
Science Snapshot: Legs for Days
Lisa Winter | Nov 2, 2022 | 1 min read
This image took 4th place at the 2022 Nikon Small World Photomicrography Competition.
Finding CAR T Cells in Solid Tumors by Single-Cell Resolution
Finding CAR T Cells in Solid Tumors at Single-Cell Resolution
The Scientist Creative Services Team in collaboration with Miltenyi Biotec | 1 min read
Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM).
Breast tissue shown in pink and yellow
Science Snapshot: Milking It
Lisa Winter | Oct 31, 2022 | 1 min read
This image took 2nd place at the 2022 Nikon Small World Photomicrography Competition.
Embryonic gecko hand
Science Snapshot: Show of Hands
Lisa Winter | Oct 28, 2022 | 1 min read
This image took the top prize at the 2022 Nikon Small World Photomicrography Competition.
Discover how to scale up cellular assays during drug discovery
High-Throughput Solutions for Lead Candidate Discovery
The Scientist Creative Services Team and Thermo Fisher Scientific | 1 min read
New technologies allow researchers to scale up assays for cellular functions.
3D imaging of organoid
Infographic: Generating Hundreds of 3D Organoid Images per Hour
Natalia Mesa, PhD | Oct 17, 2022 | 1 min read
By modifying a technique used to image single cells, researchers have managed to generate a super-resolution 3D image of a complete organoid in just seven seconds.
Cellular therapy. 3d illustration
Expert JeWell-ry Designers
Natalia Mesa, PhD | Oct 17, 2022 | 3 min read
Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.
Mapping the Brain in 3-D
Mapping the Brain in 3-D
Nathan Ni, PhD | 1 min read
3-D brain atlases help scientists better understand brain function in physiological and pathological situations.
pollen tubes releasing sperm into ovule
Science Snapshot: Go Forth and Multiply
Lisa Winter | Oct 6, 2022 | 1 min read
An honorable mention in the 2022 Nikon Small World in Motion competition shows thale cress sperm being released into the ovule.
Grayscale microscopic image of dying melanoma cells
Science Snapshot: Living Bubble Wrap
Lisa Winter | Oct 5, 2022 | 1 min read
This year’s fourth-place winner of the 2022 Nikon Small World in Motion competition shows dying melanoma cells.
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Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis
The Scientist Creative Services Team in collaboration with Sartorius | 1 min read
Discover how to image and quantitate phagocytosis in real time
purple and green microscopic view of sea anemone neurons and stinging cells
Science Snapshot: With Fronds Like These, Who Needs Anemones?
Lisa Winter | Oct 4, 2022 | 1 min read
This year’s third-place winner of the 2022 Nikon Small World in Motion competition features sea anemone cells.
Fluorescent view of a zebrafish embryo
Science Snapshot: Do the Locomotion
Lisa Winter | Sep 29, 2022 | 1 min read
The top winner of the 2022 Nikon Small World in Motion contest shows cells migrating through a zebrafish embryo.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist Creative Services Team and Thermo Fisher Scientific | 1 min read
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
Microscopy image of a cricket embryo, illuminated in green, pinched near one end, with one side full of bright green dots representing cell nuclei
How Wandering Nuclei Shape Developing Embryos
Viviane Callier | Jul 29, 2022 | 3 min read
As cricket blastoderms form, cell nuclei are pulled into an egg’s remaining empty space to form the new cell layers that will shape the developing animal.
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