Apoptosis Activity: Cell Death Establishes Itself As A Lively Research Field

Research Field Sidebars: MOST-CITED APOPTOSIS PAPERS, 1981-94 NIH FUNDING OF EXTRAMURAL GRANTS WHOSE TITLES MENTION `APOPTOSIS' WHERE APOPTOSIS RESEARCHERS GATHER The phenomenon of apoptosis--a form of programmed cell death--has sprung suddenly and dramatically into scientific consciousness. While references to apoptosis now abound in scientific literature, cell biology textbooks with copyrights prior to 1992 do not contain the term in their indexes. Before 1992, the National Institutes of He

| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Research Field Sidebars:

Before 1992, the National Institutes of Health did not list apoptosis as an area of research interest. In 1993, however, grant funding for projects whose title mentioned the word nearly doubled over the 1992 figure; funding doubled again in 1994 (see accompanying table).

And yet, when Barbara Osborne, an associate professor in the molecular and cellular biology program at the University of Massachusetts, Amherst, recently traced the development of the field, she found an erratic history, characterized by little early activity followed by booming interest. She was researching the preface for a 1995 edition of Methods in Cell Biology (San Diego, Academic Press Inc.), which she coauthored with Amherst associate professor Larry Schwartz.

"I've traced the number of publications from 1980 to the present," reports Osborne, who searched for the keyword "apoptosis." She found that "there was nothing in the early '80s. Then, in 1985 through 1987, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Ricki Lewis

    This person does not yet have a bio.

Published In

Share
TS Digest January 2025
January 2025, Issue 1

Why Do Some People Get Drunk Faster Than Others?

Genetics and tolerance shake up how alcohol affects each person, creating a unique cocktail of experiences.

View this Issue
Sex Differences in Neurological Research

Sex Differences in Neurological Research

bit.bio logo
New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Sino
New Approaches for Decoding Cancer at the Single-Cell Level

New Approaches for Decoding Cancer at the Single-Cell Level

Biotium logo
Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

Acro 

Products

Artificial Inc. Logo

Artificial Inc. proof-of-concept data demonstrates platform capabilities with NVIDIA’s BioNeMo

Sapient Logo

Sapient Partners with Alamar Biosciences to Extend Targeted Proteomics Services Using NULISA™ Assays for Cytokines, Chemokines, and Inflammatory Mediators

Bio-Rad Logo

Bio-Rad Extends Range of Vericheck ddPCR Empty-Full Capsid Kits to Optimize AAV Vector Characterization

Scientist holding a blood sample tube labeled Mycoplasma test in front of many other tubes containing patient samples

Accelerating Mycoplasma Testing for Targeted Therapy Development