Apoptosis Activity: Cell Death Establishes Itself As A Lively Research Field

Research Field Sidebars: MOST-CITED APOPTOSIS PAPERS, 1981-94 NIH FUNDING OF EXTRAMURAL GRANTS WHOSE TITLES MENTION `APOPTOSIS' WHERE APOPTOSIS RESEARCHERS GATHER The phenomenon of apoptosis--a form of programmed cell death--has sprung suddenly and dramatically into scientific consciousness. While references to apoptosis now abound in scientific literature, cell biology textbooks with copyrights prior to 1992 do not contain the term in their indexes. Before 1992, the National Institutes of He

Written byRicki Lewis
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Research Field Sidebars:

Before 1992, the National Institutes of Health did not list apoptosis as an area of research interest. In 1993, however, grant funding for projects whose title mentioned the word nearly doubled over the 1992 figure; funding doubled again in 1994 (see accompanying table).

And yet, when Barbara Osborne, an associate professor in the molecular and cellular biology program at the University of Massachusetts, Amherst, recently traced the development of the field, she found an erratic history, characterized by little early activity followed by booming interest. She was researching the preface for a 1995 edition of Methods in Cell Biology (San Diego, Academic Press Inc.), which she coauthored with Amherst associate professor Larry Schwartz.

"I've traced the number of publications from 1980 to the present," reports Osborne, who searched for the keyword "apoptosis." She found that "there was nothing in the early '80s. Then, in 1985 through 1987, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

nuclera logo

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo