Articles by Carol Wright-smith

Digital Instrument's BioScope Anyone who has ever taken the time to critically examine a walnut knows that a two-dimensional photograph fails in many respects to truly convey the unique features--the nicks, crannies, valleys, and grooves--of the walnut shell. Researchers use atomic force microscopy (AFM) to literally map the surface of inert and biological samples to obtain three-dimensional images. Whereas technological developments in microscopy1,2 have facilitated the detailed characterizatio

Microscopy Image Analysis Software Actin (red), mitochrondria (green), and nucleus (blue) signals merged by Scanalytics' IPLab Software The science of microscopy, especially how microscopic observations are made and data are collected and displayed, has come a long way since the days of Carl Zeiss. The last decade has seen a resurgence in the use of optical microscopy in basic research, due in part to advances in instrumentation. Confocal technology, high resolution solid state cameras such as