David Allis from Rockefeller University and colleagues used a biochemical pull-down assay and found that the protein WDR5, a common part of histone methyltransferase complexes, associates specifically with dimethylated H3K4 nucleosomes.

Joan Kwong Credit: Courtesy of Pat Dougherty" />Joan Kwong Credit: Courtesy of Pat Dougherty The academic two-step. For a PhD coming straight out of academia, the switch to regulatory affairs can be tough, but not impossible. "It's very doable," but it takes two transitions, David Jensen says. You'll have to start by moving from the academic bench to the industry bench, keeping in mind that the company is interested in hiring you for the research experience you have right now. O

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Reconstructing early HIV The search for immunogens delves into the virus' past By Kelly Rae Chi Related Articles 5 HIV Treatment Strategies A piggyback attack: Using the common cold to deliver an HIV vaccine The best offense? CCR5 inhibitors, with one now on the market, suggest it may be a good defense Stem cells and gene therapy: Researchers take a second look at using stem cells to treat HIV Solving the viral spike: Can structural bio

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Credit: Courtesy of Michael Skinner" /> Credit: Courtesy of Michael Skinner The paper: M.D. Anway et al., "Epigenetic transgenerational actions of endocrine disruptors and male fertility," Science, 308:1466-9, 2005. (Cited in 112 papers) The finding: A group led by Michael Skinner from Washington State University briefly exposed pregnant female rats to endocrine disruptors and found sperm defects in the F1 generation of male rats, which were passe

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The paper: J.V. Zhang et al., "Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effect on food intake." Science , 310:996-99, 2005. (Cited in 99 papers) [PUBMED] The finding: Aaron Hsueh's group from Stanford University isolated a new peptide hormone, dubbed "obestatin." Using in vitro binding studies, the group found that obestatin served as a natural ligand for

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