Machine-learning algorithms can automate the analysis of cell images and data.

Advice on how to deploy the latest techniques in your own lab

Sequencing and gene-editing advances make tracing a cell’s journey throughout development easier than ever.

How to make the most of this rapidly developing technique and a look at what's on the horizon

Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

Techniques for determining which genes or genetic variants are truly detrimental

Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.

Tips for tracing transcription in individual cells

Newer CRISPR tools for manipulating transcription will help unlock noncoding RNA’s many roles.

A growing toolbox for surveying the activity of entire genomes

Using chemogenetic tools to spur the brain into action

A new tool helps scientists better understand what happens to studies that are criticized in the literature.