Y. Ionov, M.A. Peinado, S. Malk-hosyan, D. Shibata, M. Perucho, "Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis," Nature, 363:558-61, 1993. (Cited in 108 publications through December 1994) Comments by Manuel Perucho,California Institute of Biological Research This paper represents the seminal discovery by a research team from the California Institute of Biological Research in La Jolla of an instability in simple repeated sequences o

M. Radmacher, R.W. Tillmann, H.E. Gaub, "Imaging viscoelasticity by force modulation with the atomic force microscope," Biophysical Journal, 64:735-42, 1993. (Cited in22 publications through December 1994) Comments by Manfred Radmacher,University of California, Santa Barbara The development of such high-resolution visualization instruments as the atomic force microscope (AFM) has played an important role in the study of cellular and macromolecular structures, notes biophysicist Manfred Radmac

Denis B. McWhan, Chairman of Synchrotron Light Source Assumes Associate Directorship at BNL Academic Psychologist and Health Policy Analyst, Terrie T. Wetle, New Deputy Chief Of National Institute of Aging Obituary -- Bernard Nathan Fields Denis B. McWhan, who served as the chairman of the Brookhaven National Laboratory (BNL) National Synchrotron Light Source (NSLS) since 1990, assumed the position of associate director for basic energy sciences at the Upton, N.Y., laboratory on January 1.

Over the past four years, research discoveries of possible genetic origins of human sexual orientation have touched off a tempest of controversy and debate among gay-rights advocates and their opponents, politicians, journalists-- even members of the science community. But investigators in this field, whose studies instigated the commotion, say they find themselves, for the most part, riding in the calm eye of the storm. Following are some recent, widely publicized articles on the biologica

The name of Stephen Hawking is widely recognized both within and outside the scientific community as a premier scientist and best-selling author. But he is probably as famous for having overcome great physical odds as he is for his contributions to theoretical astrophysics and cosmology: Nearly all of his major work came after he was stricken in his early 20s with the debilitating neurological condition amyotrophic lateral sclerosis (ALS). While Hawking is certainly one of the most celebrated

The unexpected death last month of Cyril Ponnamperuma, founder and director of the newly established North-South Center for Sustainable Development (NSCSD) at the University of Maryland, College Park (UMCP), has left the fledgling organization in a state of flux, according to center officials. These administrators note that Ponnamperuma's sudden passing has them scrambling to find a new director and keep the center afloat. Cyril Ponnamperuma, a professor of chemistry at the University of Mary

Industry observers maintain that capital is available for companies that have the right formula for success With almost-daily headlines chronicling funding and scientific setbacks to the biotechnology industry, the challenges for scientist- entrepreneurs contemplating making a go of their idea seem daunting, even insurmountable. Yet biotech analysts, officials, researchers, and other observers insist that, despite the depressed financial climate in the industry and investor wariness, capital

For 1950 Pennsylvania Grad, P. Roy Vagelos, It's Back To School As Chairman Of University's Board Of Trustees Japan Prize Honors A Biologist And His Field Obituary -- Betty McGee Vetter P. Roy Vagelos, who recently retired as chairman of the board of directors and chief executive officer of Merck and Co. Inc. in Whitehouse Station, N.J., assumed office as chairman of the University of Pennsylvania's board of trustees in October. He had been a member of the board since 1988. According to Va

Daniel Cosgrove, a professor of biology at Pennsylvania State University, University Park, says that this paper breaks new ground in that it gives the first insights into "the biochemical basis of one of the key processes in plant-cell growth; namely, the extension of the cell walls. "We identified proteins that make cell walls grow in surface area," he adds. Plant-cell walls are composed of large units of polysaccharides (such as

Margaret A. Hamburg, health commissioner of the New York City Department of Health, became the third member of her family to be elected to IoM. Her parents, psychiatrists David A. Hamburg, currently president of the New York-based Carnegie Corporation, and Beatrix A. Hamburg, who now serves as the president of the William T. Grant Foundation, were elected to the institute in 1971 and 1979, respectively. Margaret Hamburg recalls tha

Date : December 12, 1994 Sidebar: PHARMACEUTICAL INDUSTRY JOB STATISTICS As 1995 approaches, changing economic forces in the pharmaceutical industry are presenting its scientists with tough challenges, both professional and scientific, according to researchers, company officials, and other observers. Financial setbacks and shifting business dynamics, such as mergers and takeovers, have caused companies to drastically downsize thei

Beatrice Mintz, a senior member of the Institute for Cancer Research at the Fox Chase Cancer Center in Philadelphia, was presented with the John Scott Award during a reception on November 18 at the American Philosophical Society in Philadelphia. The prize was set up in the early 1800s by John Scott, a Scottish druggist, who entrusted the administration of the award--originally $20 and an inscribed copper medal--to the city of Phila