Articles by Duke university neurology and neurobiology professor Allen Roses and Dennis Selkoe, a professor of neurology at Harvard University, in the September 1994 issue of the Journal of Neuropathology and Experimental Neurology thoroughly explore the amyloid and apoE hypotheses: A.D. Roses, "Apolipoprotein E affects the rate of Alzheimer's disease expression: beta-amyloid burden is a secondary consequence dependent on apoE genotype and duration of disease," 53:429-37; D.J. Selkoe, "Alzheim

Following is contact information for selected publishers of journals related to the life sciences that have CD-ROM products available. Academic Press (Methods in Enzymology, NeuroImage, Virology): (800) 321-5068. American Chemical Society (Biochemistry, Journal of the American Chemical Society, and, soon, Journal of Organic Chemistry): (800) 753-4227. American Society for Biochemistry and Molecular Biology (Journal of Biological Chemistry): (301) 530-7145. American Society for Microbiology

Wave Crested? Author: Robert Finn SIDEBAR: Scientific Journals on CD-ROM When The Scientist last reported on CD-ROM-based scientific journals, the number of titles available in that format had recently surged (F. Hoke, The Scientist, Sept. 19, 1994, page 17). In the year since, there has been only a modest increase in the number of journals in the life sciences available on CD-ROM, and librarians and publishers are expressing skepticism that the number will grow much further, as online public

The biotechnology industry has shown signs recently of recovering from the doldrums of the past year, which encompassed a wave of consolidations, layoffs, and a critical cash crunch. However, as some indications arise that biotech as a whole is starting to regain investor confidence, industry analysts say that the agricultural biotech sector seems to be lagging. Ag biotech observers, including scientists in both business and academia, agree that the industry's growth has been hampered by regul

Three times a year, in conference rooms at the National Institutes of Health's Bethesda, Md., campus, about 1,440 permanent members of 100 study sections (accompanied by an annual total of about 1,800 ad hoc members) meet for two days to review 9,000 grant proposals. Critics of the system charge that it is cumbersome; needlessly hard on both reviewers and the reviewed; and rife with the potential for incompetent decisions, abuse of power, and conflicts of interest. Even its supporters acknowled

Internet Author: Robert Finn Sidebars: Access to Freeware and Shareware Archives With the life sciences becoming ever more reliant on computers, biologists find themselves constantly on the lookout for useful software. While there's no shortage of commercial vendors willing to sell full-featured packages that will perform tasks such as modeling a protein or running a flow cytometer, this software can cost many hundreds or even thousands of dollars. Fortunately, an impressive array of free or

Following are Internet addresses for accessing the archives and programs mentioned in the accompanying article: Entrez ftp://ncbi.nlm.nih.gov/entrez European Bioinformatics Institute (EBI) BioCatalog ftp://ftp.ebi.ac.uk/ gopher://ftp.ebi.ac.uk/ http://www.ebi.ac.uk/biocat/biocat.html Flow cytometry software at the University of Massachusetts, Amherst http://www.bio.umass.edu/mcbfacs/flowcat.html Bio Archive of biology software and data ftp://iubio.bio.indiana.edu/ gopher://iubio.bio.indian

The Society for Mathematical Biology P.O. Box 11283 Boulder, Colo. 80301 Fax: (303) 665-8264 E-mail: jchorbaj@mines.colorado.edu 600 members Leah Edelstein-Keshet, president Contact: Torcam Chorbajian, treasurer/secretary Bulletin of Mathematical Biology Editor: Lee Segal published by ier Science Inc., New York Phone: (212) 633-3950 * Journal of Computational Biology Editor-in-chief: David T. Kingbury published quarterly by Mary Ann Liebert Inc., Larchmont, N.Y. Phone: (914) 834-3100 *

Donald W. Genson Executive Director, B.S./MBA Program 428 Classroom Building Pennsylvania State University University Park, Pa. 16802 (814) 863-0284 E-mail: dwg9@psu.edu (The Scientist, Vol:9, #13, pg.15, June 26, 1995) (Copyright, The Scientist, Inc.)

The Scientist 9[13]:14, Jun. 26, 1995 News 'Gold-Collar' Workers By Robert Finn Sidebar Mixing Business with Science

As available academic researchjobs decline, many are questioning the wisdom of traditional maxims like 'the cream rises to the top' Rapid and accelerating changes in the structure of United States science have left many scientists bitterly disenchanted and feeling that they have been left high and dry, trapped in dead-end careers, the victims of misleading or downright bad career advice. DOUBTER: Kevin Aylesworth says that graduate advisors have a vested interest in keeping students in resear

An unfortunate number of young scientists report having been given bad career advice early in their professional lives. Faced with the choice of whether to pursue a scientific career at all, and if so, whether to aim for a career in academia, industry, government, or some other sector, potential scientists are hungry for advice and become bitterly disappointed when that advice proves incorrect. Although "incorrect" counseling may not have been mean-spirited-- indeed, it may not even have been i