The insulin growth factor 1/Akt pathway is neuroprotective in Huntington's disease and is mediated by direct phosphorylation of huntingtin.

Retention of apoB100 lipoproteins by proteoglycans immediately beneath the endothelium is a central event in early atherogenesis.

Protection against the anthrax toxin can be achieved with high affinity recombinant anti-PA antibody fragments.

mediated allergic inflammation by producing thymic stromal lymphopoietin.

B essential modifier participates in signaling pathways leading to natural killer cell cytotoxicity.

Two thirds of malignant melanomas have a mutation in the BRAF gene.

The ear wax locus is located on the same area of chromosome 16 as the gene responsible for paroxysmal kinesigenic choreoathetosis.

In humans most neocortical inhibitory GABAergic interneurons arise locally, from the cortical ventricular zone/subventricular zone.

Ciliary neurotrophic factor and leukaemia inhibitory factor have protective effects in a model of multiple sclerosis.

-synuclein in complex with 14-3-3 chaperones may be responsible for the nerve destruction in Parkinson's disease.

is expressed in both normal and malignant spermatogenic cells and its overexpression is correlated to seminoma development.

Red blood cells use nitric oxide to respond to changes in oxygen tension with graded vasodilator and vasoconstrictor activity.