-synuclein in complex with 14-3-3 chaperones may be responsible for the nerve destruction in Parkinson's disease.
Parkinson's disease (PD) is caused by a progressive deterioration of the neurons that control movement and contain dopamine, but the mechanism by which dopaminergic neurons are selectively lost has been unclear. In June
Xu
In addition, they found that soluble protein complexes that contain α-synuclein and 14-3-3 protein chaperones, mediate dopamine-dependent neurotoxicity in PD.
"Xu et al. provide a strong and ...
Add The Scientist as a preferred Google source to see more of our trusted coverage.
When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.
View this Issue
Explore strategies for improving recombinant adeno-associated virus production in transient HEK293 suspension cultures while maintaining vector quality and supporting scalable viral vector manufacturing.
Discover how tissue-resident memory T cells develop within the respiratory tract and how these findings are advancing respiratory virus immunity, vaccine research, and high-throughput immune profiling.
Bench architecture, primer design, and liquid handling set an assay's limit as throughput climbs.
Explore emerging mechanisms of immune checkpoint inhibitor resistance in hepatocellular carcinoma (HCC) and how combination immunotherapy strategies may improve antitumor immune responses and patient-specific treatment approaches.
European customers can now subscribe to Sino Biological’s newsletter to receive a special gift and unlock access to EliteScience benefits.
Sino Biological’s trial program enables qualified customers to evaluate SuperNuclease Pro in their specific bioprocessing applications, facilitating faster technology assessment and informed decision-making during process development
This release expands on Sino Biological's comprehensive Tau protein product portfolio, designed to accelerate neurodegenerative disease research.
Resipher measures cellular respiration (OCR) continuously in standard 96-well plates inside your incubator, for days to weeks. No media swaps, dyes, or transfers. A live-cell functional readout for drug safety, metabolism, and mitochondrial health.
