NF-κB signaling has a pivotal role in innate immunity with uncontrolled NF-κB activation contributing to B cell lymphoma development. However, the mechanisms that regulate NF-κB signaling in B-lymphocytes have been poorly understood. In 15 July advanced online
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"Our data suggest that a combination of standard chemotherapy with drugs targeting the PKC-βκ–dependent NF-κκB survival pathway may...