BellBrook Labs was awarded a Phase I Small Business Innovative Research (SBIR) grant of $353,000 from the National Institute of Alcohol Abuse and Alcoholism for pharmacological validation of GIV, a nonreceptor guanine nucleotide exchange factor (GEF), as a therapeutic target for liver fibrosis. BellBrook will use proprietary high throughput GTPase assay methods to identify small molecule inhibitors of GIV and test them in disease models, setting the stage for a targeted drug discover effort in Phase II.
BellBrook Labs received a Phase I Small Business Innovative Research (SBIR) grant from the National Institute on Alcohol Abuse and Alcoholism to use their proprietary Transcreener GDP GTPase assay platform for the pharmacological validation of a promising new therapeutic target for liver fibrosis. The $353,000 grant will allow principal investigator, Dr. Steve Hayes, to use high throughput screening (HTS) of small molecules to identify GIV inhibitors and test them in cellular models for ...
