Skip to main content

Botanical Biopharming

Green-thumbed biotechs say they can use plants to make drugs faster, cheaper, and better than top pharmaceutical companies.

Written byMegan Scudellari
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00

In 2001, ProdiGene was a poster child for the plant biotechnology industry. A privately owned biotech in College Station, Texas, ProdiGene was the first to successfully commercialize a product made from a transgenic plant—a protein called trypsin produced in corn kernels and sold to the pharmaceutical industry for mammalian cell culturing. They also had more than 18 other plant-made products in development, including vaccines for traveler’s diarrhea, hepatitis B, and AIDS. That spring, the MIT Technology Review voted ProdiGene’s oral vaccine patent one of the “five patents that will transform business and technology.”

But a year later, things began to spiral downhill. In September 2002, the US Department of Agriculture ordered ProdiGene to destroy 155 acres (63 hectares) of corn in Iowa that may have cross-pollinated with a nearby test site of ProdiGene’s transgenic corn. Then in October, the USDA seized 500,000 bushels of soybeans contaminated by ProdiGene’s corn in ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Published In

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Improving rAAV Production for Viral Vector Manufacturing

Improving rAAV Production for Viral Vector Manufacturing

cytiva logo
Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Scientist holding a clear 384-well PCR microplate in a laboratory

What Dictates PCR Success Before Amplification Begins?

Integra Logo
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems

Products

Sino Biological Logo

Sino Biological Launches European Newsletter Campaign with Exclusive Welcome Gifts

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo