Brains in Action

An inspiring lecturer turned Marcus Raichle’s focus from music and history to science. Since then, he has pioneered the use of imaging to study how our brains function.

Written byAnna Azvolinsky
| 9 min read

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MARCUS E. RAICHLE
Professor of Radiology, Neurology, Neurobiology and Biomedical Engineering Washington University School of Medicine, St. Louis
WASHINGTON UNIVERSITY
Marcus Raichle was a University of Washington junior majoring in history and political science when he took his first biology class to fulfill a science requirement. Introduction to zoology as taught by marine biologist Dixy Lee Ray was so transformative that he immediately switched his major to premed, says Raichle, who had to start his science education from scratch. After a year’s setback because of a misplaced invite for a medical school interview, Raichle was accepted at the University of Washington School of Medicine . “I felt like a fish out of water, surrounded by people who must have gotten out of the crib and said, ‘I want to go to medical school.’”

Raichle became fascinated by neuroscience. “I read our neuroanatomy textbook cover to cover, and I still have it,” he says. Raichle was particularly inspired by his teacher and subsequent mentor, Fred Plum, at that time the youngest person to chair a neurology department in the U.S. “He asked us in class what the relationship was between a pain and a tickling sensation, and I happened to know. Even though I was shy and not in the habit of raising my hand, I gave an answer that he appeared pleased with, and from that moment on, I felt like, ‘OK, I have arrived.’”

“I think, for better or worse, imaging has become the face of neuroscience.”

Since graduating from medical school in 1964, Raichle has been ...

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    Anna Azvolinsky received a PhD in molecular biology in November 2008 from Princeton University. Her graduate research focused on a genome-wide analyses of genomic integrity and DNA replication. She did a one-year post-doctoral fellowship at Memorial Sloan Kettering Cancer Center in New York City and then left academia to pursue science writing. She has been a freelance science writer since 2012, based in New York City.

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