The mechanisms underlying the innate immune system are highly conserved from flies to mammals. In the December 18 Proceedings of the National Academy of Sciences, Phil Irving and colleagues describe a genome-wide screen for genes induced in Drosophila following infection with bacteria or fungi (Proc Natl Acad Sci USA 2001, 98:15119-15124).They performed oligonucleotide-array gene-profiling analysis on material from flies inoculated with Gram-negative or Gram-positive bacteria or with the fungi B
The mechanisms underlying the innate immune system are highly conserved from flies to mammals. In the December 18
They performed oligonucleotide-array gene-profiling analysis on material from flies inoculated with Gram-negative or Gram-positive bacteria or with the fungi
Nearly half of the immune-induced genes are of unknown function, providing many new clues into innate ...
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