No effective drug currently exists to treat brain injury and the mechanisms that control post-trauma events remain largely unknown. In October 4 Nature, David Panikashvili and colleagues from the Hebrew University, Jerusalem, show that the cannabinoid, 2-arachidonoyl glycerol (2-AG) is part of an endogenous system that protects the brain in the period following traumatic injury.Panikashvili et al. observed that after closed head injury in mice the level of endogenous 2-AG was significantly eleva
No effective drug currently exists to treat brain injury and the mechanisms that control post-trauma events remain largely unknown. In October 4
Panikashvili
They suggest that this interaction leads to 2-AG suppression of the formation of reactive oxygen ...
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