Cesarean Section Results in Heavier Mouse Pups

Vaginal birth leads to changes in the development of offsprings’ microbiomes not seen among mice born via C-section, which researchers suspect might contribute to the weight differences.

| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ISTOCK, DENBOMAMice born by Cesarean section grow up to be heftier than their counterparts born vaginally, a new study shows. The result, published today (October 11) in Science Advances, suggests the birthing procedure messes with the mice’s gut bacteria, making them more prone to weight gain.

“C-section leads to increased body weight gain in a mammal model. In humans, there is epidemiological evidence that this happens too,” study coauthor Maria Gloria Dominguez-Bello of New York University School of Medicine tells The Scientist in an email. The results join a mixed bag of studies in both animals and humans that have yet to determine conclusively the health effects of babies’ modes of delivery.

In the paper, Dominguez-Bello and colleagues note that C-section surgery is sometimes a lifesaving procedure, necessary in 10 percent to 15 percent of births to avoid death of the mother, child, or both. C-sections, however, have increased, with doctors in some regions of the world performing them 43 percent of the time. In the U.S., C-sections account for 32 ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

fujirebio-square-logo

Fujirebio Receives Marketing Clearance for Lumipulse® G pTau 217/ β-Amyloid 1-42 Plasma Ratio In-Vitro Diagnostic Test

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours