Live Webinar
Wednesday, December 8, 2021
11:00 AM - 12:00 PM Eastern Time
Viral and host cell proteases play an important role in SARS-CoV-2 infection and replication. Viral proteases cleave cellular proteins to divert the host protein synthesis machinery to make viral proteins. Additionally, viral entry requires S protein cleavage by cellular proteases. Using mass spectrometry, researchers identify new protein fragments generated after the proteolytic cleavage of viral and cellular proteins. In this webinar brought to you by Thermo Fisher Scientific, Edward Emmott will discuss the identification and importance of previously unknown cleavage sites in SARS-CoV-2 proteins, including S protein and nucleocapsid, and new protease substrates essential for efficient SARS-CoV-2 replication in cells.
Topics to be Covered
- Mass spectrometry approaches to study proteolytic cleavage during SARS-CoV-2 infection
- Functions of viral and cellular proteases during viral infection
- Multiplexing protein N-terminal sequencing workflows
Meet the Speaker:
Edward Emmott,...
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