Who: BD (Matrigel), Trevigen (Cultrex).
Uses and Perks: Supports the growth and differentiation of cells and tissues. Recapitulates the morphology and viscoelasticity of the ECM. Can be remodeled by cells
Drawbacks: Expensive, composition is variable.
How much: About $200 for 10 ml. (Brugge uses 40
Who: Millipore, BD, Sigma, and other suppliers.
Uses and Perks: Frequently used to study migration and invasion. Can be remodeled by cells. Often used in combination with each other, or "spiked" into other matrices.
Drawbacks: Not always interchangeable. For example, even among collagen 1, glycosylation (and solubility) varies by source. Properties differ between native and denatured proteins.
How much: About $130 for 100 mg of rat tail-derived collagen 1.
Who: BD (PuraMatrix Peptide Hydrogel), Glycosan (Extracel, HyLink)
Uses and Perks: Fully characterized alternatives to BME. Also used as a scaffold for tissue growth and repair. Often ...
