June 2008

Hazel Barton with a gypsum formation. Credit: Courtesy of Dave Bunnell / Under Earth Images" />Hazel Barton with a gypsum formation. Credit: Courtesy of Dave Bunnell / Under Earth Images Three years ago, Hazel Barton, a biologist from Northern Kentucky University, traveled to southern Venezuela to star in an Animal Planet documentary entitled "The Real Lost World." While there, she visited Mount Roraima, the largest

Torch Ginger flower in which a new species of Caenorhabditis was found. Credit: Courtesy of Valérie Robert" />Torch Ginger flower in which a new species of Caenorhabditis was found. Credit: Courtesy of Valérie Robert In December 2007, Marie-Anne Félix was taking a small cruise along the southwestern coast of India when she found herself docked in a remote lagoon in the backwate

For Mike Rossner, the impetus to look for image manipulation came suddenly. In 2002, when Rossner was the managing editor at the Journal of Cell Biology, the journal switched to completely electronic submissions. One of the first submissions after the change contained unusable PowerPoint images. In the process of reformatting, Rossner, now executive director of Rockefeller Press, di

A monkey at the CNPRC Credit: Courtesy of Katherine West / CNPRC" />A monkey at the CNPRC Credit: Courtesy of Katherine West / CNPRC It was the spring of 2005, and some of the rhesus monkeys at the California National Primate Research Center were behaving oddly. Specifically, they were climbing to the top of their chain-linked cages and flipping over backwards, over and over. Others were pacing frantically

var FO = { movie:"http://www.the-scientist.com/supplementary/flash/54719/worms.swf", width:"520", height:"680", majorversion:"8", build:"0", xi:"true"}; UFO.create(FO, "ufoDemo"); The worm hunter in India Please download the Adobe Flash Player to view this content:

var FO = { movie:"http://images.the-scientist.com/supplementary/flash/autisticMonkey/Autism.swf", width:"400", height:"550", majorversion:"8", build:"0", xi:"false"}; UFO.create(FO, "ufoDemo"); Video: Autistic Monkeys?In our June issue, staff writer Andrea Garwrylewski writes about how some of the rhesus monkeys at the California National Primate Research Center whose mothers had been given an injection of autism-associated antibodies were behaving oddly. Specifically

Ravi Allada (left) and Kevin Keegan (right) getting into the rhythm of their analysis. Credit: Courtesy of Ravi Allada" />Ravi Allada (left) and Kevin Keegan (right) getting into the rhythm of their analysis. Credit: Courtesy of Ravi Allada In October 2004, just as the clocks were changing in Illinois, the focus of Kevin Keegan's graduate work on circadian clocks was changing, too. Keegan, a

The Citric Acid CycleThe reductive citric acid cycle behaves like a chemical hurricane. Carbon atoms from CO 2 (yellow and orange) attach at either end of molecules. As the cycle proceeds (counterclockwise), they are drawn toward the interior (red) until the molecule splits at the top of the cycle, creating two smaller molecules (curved arrow), which then repeat the cycle. var FO = { movie:"http://images.the-scientist.com/content/images/articles/54716/infographic

Before Darwin © Michele David, Lava Pool, 2001 How the earth went from lifeless to life. By Eric SmithUnderpainting by Michele Smith Illustrations by Bryan Satalino Related Articles 1 in 1865 that traits do not mix like paint when they are handed down from parents to offspring, but rather are shuffled like cards. The concept of the unmixable source of a trait (say, whether peas would be smooth or wrinkled) was given the name gene, and Mendel's im

Infographic: Three Obesity Drugs By Edyta Zielinska var FO = { movie:"http://images.the-scientist.com/content/images/articles/54718/drugs.swf", width:"520", height:"400", majorversion:"8", build:"0", xi:"false"}; UFO.create(FO, "ufoDemo"); Please download the Adobe Flash Player to view this content: Related Articles Diverting a Diet Drug The Good FatThe Future of the FDAThe Trouble with Tech Transfer var FO = { mov

Diverting a Diet Drug How did a controversial product become the first weight-loss drug to be available without a prescription? By Fran Hawthorne Illustrations by Bill Sanderson Related Articles 1 "That was another big Aha! moment, because we didn't know that study existed," Burton says. The researchers found that people who took orlistat (the generic name for Xenical) experienced a 37% lower risk of type 2 diabetes. According to the report, "the overal

Best Places to Work 2008: Demographics & Most Important Factors Factors you Ranked Most Important 1 Job Satisfaction My work gives me personal satisfaction. 2 Job Satisfaction I feel that my contributions to the team are appreciated and that the team works well together. 3 Integrity My company sets and adheres to high ethical standards. 4 Research Environment My company provides the equipment and services I nee

var FO = { movie:"http://www.the-scientist.com/supplementary/flash/54703/bptw_industry08.swf", width:"520", height:"680", majorversion:"8", build:"0", xi:"true"}; UFO.create(FO, "ufoDemo"); Slideshow: Best Places to Work in Industry Please download the Adobe Flash Player to view this content: Related Articles New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic Char

Best Places to Work 2008: Industry Top Institutions PDF Related Articles Best Places to Work in Industry 2008 New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic Charts Ranking Tables: Top 30 Top Large Top Small Downloadable PDFs In our June issue, review the companies that ranked at the top of our annual Best Places to Work for Industry survey. Here, download the 2008 Top In

Best Places to Work Postdoc 2008: Top Large Companies In our June issue, review the companies that ranked at the top of our annual Best Places to Work for Industry survey. Click here to view the printable PDF.Click on the thumbnail to use the interactive chart. Resize the rows or scroll within the chart to view category. Related Articles New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic

Best Places to Work Postdoc 2008: Top Small Companies In our June issue, review the companies that ranked at the top of our annual Best Places to Work for Industry survey. Click here to view the printable PDF.Click on the thumbnail to use the interactive chart. Resize the rows or scroll within the chart to view category. Related Articles New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic

Best Places to Work Postdoc 2008: Top 30 Companies In our June issue, review the companies that ranked at the top of our annual Best Places to Work for Industry survey. Click here to view the printable PDF.Click on the thumbnail to use the interactive chart. Resize the rows or scroll within the chart to view category. Related Articles New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic Ch

Best Places to Work 2008: Industry courtesy of Sigma-Aldrich The competitive world of industry fosters an appetite to get ahead. In our sixth annual survey, we uncover the recipe for a successful workplace. By Elie Dolgin Best Places to Work 2008: Industry New opportunities at Organon Lone-star pharma Survey Methodology Slideshow: BPTW 2008 Industry Demographic ChartsRanking Tables: Top 30 Top Large Top Small Downloadable PDFs The c

Organon headquarters in Oss, the Netherlands Credit: reproduced with permission of nv Organon / all rights reserved" />Organon headquarters in Oss, the Netherlands Credit: reproduced with permission of nv Organon / all rights reserved Organon ranked seventh among large companies in this year's Best Places to Work in Industry survey - its first year on our charts. Despite being acquired last f

A researcher at Lexicon Pharmaceuticals Credit: Courtesy of Lexicon Pharmaceuticals" />A researcher at Lexicon Pharmaceuticals Credit: Courtesy of Lexicon Pharmaceuticals Thirty miles north of Houston, texas - and a world away from the biopharmaceutical industry's hubs in California and New Jersey - sits The Woodlands, a sylvan community and home to the headquarters of Lexicon Pharmaceuticals. The compan

The Scientist Readers' Survey Methodology Best Places to Work in Industry 2008Survey Form: A web-based survey was posted on The Scientist web site from January 15 to March 7, 2008. Results were collected and collated automatically.Click here for survey questionsInvitations: E-mail invitations were sent to readers of The Scientist and registrants on The Scientist web site who identified themselves as working in commercial or industrial companies. Responses: 1929 useable an

Sean Eddy used his decades' experience playing video games to design software that found an entire new class of genes. And he's still looking.

Preclinical is the step between discovery research and clinical trials. Because clinical trials are so expensive, preclinical research is an important step in selecting only those drug candidates that have the greatest chance of success. This work involves testing drug candidates in cell lines and in animal models to demonstrate efficacy and safety.

Regulatory affairs liaisons communicate directly with the FDA throughout the drug development process and manage the drug application filings. They play an important role in providing strategic regulatory advice for the company's drug development programs.

In process development, you produce chemical or biological drug candidates at small scale for clinical trials, and develop synthesis and bioprocessing methods for scale-up into commercial manufacturing. It is a growing area that attracts chemists, microbiologists, biochemists, and molecular biologists.

Project managers oversee and coordinate the efforts of multidisciplinary projects so teams complete their work in an efficient, timely, and focused manner. This involves leading and managing a team of accomplished people who don't report directly to you, orchestrating schedules, staying within budgets, and handling a variety of personalities.