Preclinical Research

Preclinical is the step between discovery research and clinical trials. Because clinical trials are so expensive, preclinical research is an important step in selecting only those drug candidates that have the greatest chance of success. This work involves testing drug candidates in cell lines and in animal models to demonstrate efficacy and safety.

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Personality test
• Do you like working on the practical side of drug discovery? This area requires creative-minded scientists capable of innovative thought, yet capable of working in a more directed and collaborative environment.
• Are you a meticulous record keeper? Your results could become part of regulatory filings.
• Are you able to speak the language of in vitro and in vivo scientists, and clinicians? All are important in this role.

Pros • Still scientific. Even though it's a bit more applied, the science is still the biggest part of the job, and you are relied on as the expert in your area. • More than discovery. As a preclinical scientist, you will be more tuned into what's happening in clinical, manufacturing, and regulatory areas - exposure that discovery scientists rarely have. • Focus on best ideas. You will be working on only those drugs that have passed the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Toby Freedman

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer