Dendritic cells (DCs) interact with naïve T cells in the presence of antigens to initiate primary immune responses, but it is know known whether this interaction also occurs in the absence of antigens. Two reports in October
Takayuki Kondo and colleagues from the US National Institutes of Health investigated the DC-mediated signal from the T cell surface to the nucleus and found a pattern of activation in T cells that correlates with increased
In a separate study, Patrick Revy and colleagues from Institut Cochin de Génétique Moléculaire, Paris, found that in the absence...